Literature DB >> 18784936

Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP): 18-month experience with telemedicine screening.

Ruwan A Silva1, Yohko Murakami, Atul Jain, Jarel Gandhi, Eleonora M Lad, Darius M Moshfeghi.   

Abstract

PURPOSE: To report the 18-month experience of the Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP) telemedicine initiative.
DESIGN: Retrospective analysis of the SUNDROP archival data between 1 December 2005 and 30 May 2007, evaluating this new diagnostic technology for ROP screening. PARTICIPANTS: All 97 consecutively enrolled infants in the SUNDROP network.
METHODS: All patients were screened using the RetCam II, and evaluated by the SUNDROP reading center at Stanford University. Nurses were trained to obtain five images in each eye. All patients were screened by an ophthalmologist trained in diagnosing ROP within 1 week of discharge from the hospital. MAIN OUTCOME MEASURES: Outcomes included referral-warranted disease, need for treatment, and anatomic outcomes. Referral-warranted disease was defined as any Early Treatment Retinopathy of Prematurity Disease Type 2 or greater, threshold disease, any plus disease, and any stage 4 or higher disease.
RESULTS: In the initial 18-month period, the SUNDROP telemedicine screening initiative has not missed any referral-warranted disease for ROP. A total of 97 infants (194 eyes) were enrolled, resulting in 443 unique examinations and 4,929 unique images. The mean birth weight of the infants was 1,186.9 grams, with a mean gestational age at birth of 28.9 weeks. Seven infants were identified with referral-warranted disease; six patients underwent laser photocoagulation and completely regressed. The one remaining patient regressed spontaneously, and did not require intervention. Calculated sensitivity and specificity was 100% and 98.9% respectively. No patient progressed to retinal detachment or other adverse outcome. Inadequate exposure, artifact, poor visualization of the periphery, and lack of a complete standardized image set in some patients were identified as areas requiring further assessment.
CONCLUSIONS: The SUNDROP telemedicine screening initiative for ROP has proven to have a high degree of sensitivity and specificity for identification of referral-warranted disease. Training was easily implemented. All cases of referral-warranted disease were captured. There were no adverse outcomes.

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Mesh:

Year:  2008        PMID: 18784936     DOI: 10.1007/s00417-008-0943-z

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  53 in total

1.  Telemedicine based screening of infants at risk for retinopathy of prematurity.

Authors:  B Lorenz; M Bock; H M Müller; N A Massie
Journal:  Stud Health Technol Inform       Date:  1999

2.  Telephotoscreening to detect retinopathy of prematurity: preliminary study of the optimum time to employ digital fundus camera imaging to detect ROP.

Authors:  Kimberly G Yen; Ditte Hess; Barbara Burke; Rose Anne Johnson; William J Feuer; John T Flynn
Journal:  J AAPOS       Date:  2002-04       Impact factor: 1.220

3.  Mass screening: theory and ethics.

Authors:  D Mant; G Fowler
Journal:  BMJ       Date:  1990-04-07

4.  Systemic effects of screening for retinopathy of prematurity.

Authors:  D E Laws; C Morton; M Weindling; D Clark
Journal:  Br J Ophthalmol       Date:  1996-05       Impact factor: 4.638

5.  Screening examination of premature infants for retinopathy of prematurity.

Authors: 
Journal:  Pediatrics       Date:  2006-02       Impact factor: 7.124

6.  Telemedical retinopathy of prematurity diagnosis: accuracy, reliability, and image quality.

Authors:  Michael F Chiang; Lu Wang; Mihai Busuioc; Yunling E Du; Patrick Chan; Steven A Kane; Thomas C Lee; David J Weissgold; Audina M Berrocal; Osode Coki; John T Flynn; Justin Starren
Journal:  Arch Ophthalmol       Date:  2007-11

7.  Accuracy and reliability of remote retinopathy of prematurity diagnosis.

Authors:  Michael F Chiang; Jeremy D Keenan; Justin Starren; Yunling E Du; William M Schiff; Gaetano R Barile; Joan Li; Rose Anne Johnson; Ditte J Hess; John T Flynn
Journal:  Arch Ophthalmol       Date:  2006-03

8.  Screening for retinopathy of prematurity--a comparison between binocular indirect ophthalmoscopy and RetCam 120.

Authors:  Parag K Shah; V Narendran; V R Saravanan; A Raghuram; Abhijit Chattopadhyay; Maithreyi Kashyap
Journal:  Indian J Ophthalmol       Date:  2006-03       Impact factor: 1.848

9.  A comparison of laser photocoagulation with cryotherapy for threshold retinopathy of prematurity at 10 years: part 1. Visual function and structural outcome.

Authors:  Eugene Y J Ng; Brian P Connolly; J Arch McNamara; Carl D Regillo; James F Vander; William Tasman
Journal:  Ophthalmology       Date:  2002-05       Impact factor: 12.079

Review 10.  Telemedicine applications in pediatric cardiology.

Authors:  C Sable
Journal:  Minerva Pediatr       Date:  2003-02       Impact factor: 1.312

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  12 in total

1.  Detection of clinically significant retinopathy of prematurity using wide-angle digital retinal photography: a report by the American Academy of Ophthalmology.

Authors:  Michael F Chiang; Michele Melia; Angela N Buffenn; Scott R Lambert; Franco M Recchia; Jennifer L Simpson; Michael B Yang
Journal:  Ophthalmology       Date:  2012-04-27       Impact factor: 12.079

Review 2.  The regionalization of pediatric health care.

Authors:  Scott A Lorch; Sage Myers; Brendan Carr
Journal:  Pediatrics       Date:  2010-11-01       Impact factor: 7.124

3.  Telemedicine approaches to evaluating acute-phase retinopathy of prematurity: study design.

Authors: 
Journal:  Ophthalmic Epidemiol       Date:  2014-06-23       Impact factor: 1.648

Review 4.  Computer-based image analysis for plus disease diagnosis in retinopathy of prematurity.

Authors:  Leah A Wittenberg; Nina J Jonsson; R V Paul Chan; Michael F Chiang
Journal:  J Pediatr Ophthalmol Strabismus       Date:  2011-03-01       Impact factor: 1.402

Review 5.  Telemedicine for retinopathy of prematurity diagnosis: evaluation and challenges.

Authors:  Grace M Richter; Steven L Williams; Justin Starren; John T Flynn; Michael F Chiang
Journal:  Surv Ophthalmol       Date:  2009-08-08       Impact factor: 6.048

Review 6.  Telemedicine: Pediatric Applications.

Authors:  Bryan L Burke; R W Hall
Journal:  Pediatrics       Date:  2015-07       Impact factor: 7.124

7.  Parental perceptions toward digital imaging and telemedicine for retinopathy of prematurity management.

Authors:  Joo-Yeon Lee; Yunling E Du; Osode Coki; John T Flynn; Justin Starren; Michael F Chiang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-09-23       Impact factor: 3.117

8.  Speed of telemedicine vs ophthalmoscopy for retinopathy of prematurity diagnosis.

Authors:  Grace M Richter; Grace Sun; Thomas C Lee; R V Paul Chan; John T Flynn; Justin Starren; Michael F Chiang
Journal:  Am J Ophthalmol       Date:  2009-04-18       Impact factor: 5.258

9.  Diagnostic accuracy of a digital fundus photographic system for detection of retinopathy of prematurity requiring treatment (ROP-RT).

Authors:  Phanthipha Wongwai; Sirinya Suwannaraj; Somkiat Asawaphureekorn
Journal:  PLoS One       Date:  2018-07-31       Impact factor: 3.240

Review 10.  Imaging the pediatric retina: An overview.

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