Literature DB >> 18762843

Carbene complexes of gold: preparation, medical application and bonding.

Helgard G Raubenheimer1, Stephanie Cronje.   

Abstract

New preparative methods for gold carbene complexes have been developed and older ones modified to prepare compounds with specific inherent properties for targeted applications. One of the important areas of application that has grown rapidly and wherein carbene complexes are increasingly significant falls within the field of medicine. Sophisticated theoretical calculations have accompanied many synthetic studies. These aspects are covered in this critical review (65 references).

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Year:  2008        PMID： 18762843     DOI： 10.1039/b708636a

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN： 0306-0012            Impact factor:   54.564


  14 in total

1.  Synthesis of Highly Stable 1,3-Diaryl-1H-1,2,3-triazol-5-ylidenes and their Applications in Ruthenium-Catalyzed Olefin Metathesis.

Authors:  Jean Bouffard; Benjamin K Keitz; Ralf Tonner; Vincent Lavallo; Gregorio Guisado-Barrios; Gernot Frenking; Robert H Grubbs; Guy Bertrand
Journal:  Organometallics       Date:  2011-03-09       Impact factor: 3.876

Review 2.  N-Heterocyclic Carbene Complexes in C-H Activation Reactions.

Authors:  Qun Zhao; Guangrong Meng; Steven P Nolan; Michal Szostak
Journal:  Chem Rev       Date:  2020-01-22       Impact factor: 60.622

Review 3.  The medicinal applications of imidazolium carbene-metal complexes.

Authors:  Khadijah M Hindi; Matthew J Panzner; Claire A Tessier; Carolyn L Cannon; Wiley J Youngs
Journal:  Chem Rev       Date:  2009-08       Impact factor: 60.622

4.  Cytotoxicity of cyclometalated platinum complexes based on tridentate NCN and CNN-coordinating ligands: remarkable coordination dependence.

Authors:  Dileep A K Vezzu; Qun Lu; Yan-Hua Chen; Shouquan Huo
Journal:  J Inorg Biochem       Date:  2014-02-03       Impact factor: 4.155

5.  N-Heterocyclic Carbene-Gold(I) Complexes Conjugated to a Leukemia-Specific DNA Aptamer for Targeted Drug Delivery.

Authors:  Weijia Niu; Xigao Chen; Weihong Tan; Adam S Veige
Journal:  Angew Chem Int Ed Engl       Date:  2016-06-17       Impact factor: 15.336

Review 6.  Organometallic anticancer compounds.

Authors:  Gilles Gasser; Ingo Ott; Nils Metzler-Nolte
Journal:  J Med Chem       Date:  2010-11-15       Impact factor: 7.446

7.  Synthesis of axially chiral oxazoline-carbene ligands with an N-naphthyl framework and a study of their coordination with AuCl·SMe(2).

Authors:  Feijun Wang; Shengke Li; Mingliang Qu; Mei-Xin Zhao; Lian-Jun Liu; Min Shi
Journal:  Beilstein J Org Chem       Date:  2012-05-11       Impact factor: 2.883

8.  One-carbon extrusion from a tetraazafulvalene. Isolation of aldehydes and a study of their origin.

Authors:  John A Murphy; Franziska Schoenebeck; Neil J Findlay; Douglas W Thomson; Sheng-ze Zhou; Jean Garnier
Journal:  J Am Chem Soc       Date:  2009-05-13       Impact factor: 15.419

9.  Biological Screening of Newly Synthesized BIAN N-Heterocyclic Gold Carbene Complexes in Zebrafish Embryos.

Authors:  Muhammad Farooq; Nael Abu Taha; Rachel R Butorac; Daniel Anthony Evans; Ahmed A Elzatahry; Elsayed Ahmed Elsayed; Mohammad A M Wadaan; Salem S Al-Deyab; Alan H Cowley
Journal:  Int J Mol Sci       Date:  2015-10-16       Impact factor: 5.923

10.  Antiproliferative effects of two gold(I)-N-heterocyclic carbene complexes in A2780 human ovarian cancer cells: a comparative proteomic study.

Authors:  Francesca Magherini; Tania Fiaschi; Elisa Valocchia; Matteo Becatti; Alessandro Pratesi; Tiziano Marzo; Lara Massai; Chiara Gabbiani; Ida Landini; Stefania Nobili; Enrico Mini; Luigi Messori; Alessandra Modesti; Tania Gamberi
Journal:  Oncotarget       Date:  2018-06-15
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