| Literature DB >> 18757917 |
Juan Huang1, Wenke Zhou, Annie M Watson, Yuh-Nung Jan, Yang Hong.
Abstract
In this report, we describe several approaches to improve the scalability and throughput of major genetic crosses in ends-out gene targeting. We generated new sets of targeting vectors and fly stocks and introduced a novel negative selection marker that drastically reduced the frequency of false-positive targeting candidates.Entities:
Mesh:
Year: 2008 PMID: 18757917 PMCID: PMC2535722 DOI: 10.1534/genetics.108.090563
Source DB: PubMed Journal: Genetics ISSN: 0016-6731 Impact factor: 4.562