| Literature DB >> 1871958 |
T Takeuchi1, I Kubonishi, Y Ohtsuki, I Miyoshi.
Abstract
A monoclonal antibody, termed K-20, was generated against an anaplastic thymic carcinoma cell line, Ty-82. Subcapsular thymic epithelial cells of the thymus and blood vessels in various organs were shown to react with the K-20 monoclonal antibody by immunohistochemical staining. Immunofluorescent study revealed that various haematopoietic fresh cells and cell lines did not show any significant reactivity with K-20, except for one Epstein-Barr-virus-carrying lymphoma cell line (SP-50B). Western immunoblotting and affinity purification procedure revealed that K-20 was directed to a protein with a molecular weight of 28 kDa. K-20 is unique in its restrictive reactivity with human subcapsular thymic epithelial cells.Entities:
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Year: 1991 PMID： 1871958 DOI： 10.1007/bf01600229
Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398