Literature DB >> 18694925

Members of the S100 family bind p53 in two distinct ways.

Maria Rosario Fernandez-Fernandez1, Trevor J Rutherford, Alan R Fersht.   

Abstract

p53 binds to some members of the S100 family (S100B, S100A4, S100A2, and S100A1). We previously showed that both S100B and S100A4 bind to the p53 tetramerization domain, and consequently control its oligomerization state, but only S100B binds to the C-terminal negative regulatory domain (NRD). Here, we investigate other binding partners for p53 within the S100 family (S100A6 and S100A11), and show that binding to the p53 tetramerization domain seems to be a general feature of the S100 family, while binding to the NRD is a characteristic of a subset of the family.

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Year:  2008        PMID： 18694925      PMCID： PMC2548378          DOI： 10.1110/ps.035527.108

Source DB:  PubMed          Journal:  Protein Sci        ISSN： 0961-8368            Impact factor:   6.725


  26 in total

1.  Structure of the negative regulatory domain of p53 bound to S100B(betabeta).

Authors:  R R Rustandi; D M Baldisseri; D J Weber
Journal:  Nat Struct Biol       Date:  2000-07

2.  Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction.

Authors:  M Grigorian; S Andresen; E Tulchinsky; M Kriajevska; C Carlberg; C Kruse; M Cohn; N Ambartsumian; A Christensen; G Selivanova; E Lukanidin
Journal:  J Biol Chem       Date:  2001-03-05       Impact factor: 5.157

3.  Identification of binding domains in the sodium channel Na(V)1.8 intracellular N-terminal region and annexin II light chain p11.

Authors:  W-Y Louisa Poon; Misbah Malik-Hall; John N Wood; Kenji Okuse
Journal:  FEBS Lett       Date:  2004-01-30       Impact factor: 4.124

4.  Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.

Authors:  J Baudier; C Delphin; D Grunwald; S Khochbin; J J Lawrence
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

5.  Recognition of the tumor suppressor protein p53 and other protein targets by the calcium-binding protein S100B.

Authors:  Paul T Wilder; Jing Lin; Catherine L Bair; Thomas H Charpentier; Dong Yang; Melissa Liriano; Kristen M Varney; Andrew Lee; Amos B Oppenheim; Sankar Adhya; France Carrier; David J Weber
Journal:  Biochim Biophys Acta       Date:  2006-08-25

6.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

7.  Binding to intracellular targets of the metastasis-inducing protein, S100A4 (p9Ka).

Authors:  H Chen; D G Fernig; P S Rudland; A Sparks; M C Wilkinson; R Barraclough
Journal:  Biochem Biophys Res Commun       Date:  2001-09-07       Impact factor: 3.575

8.  Inhibition of p53 transcriptional activity by the S100B calcium-binding protein.

Authors:  J Lin; M Blake; C Tang; D Zimmer; R R Rustandi; D J Weber; F Carrier
Journal:  J Biol Chem       Date:  2001-07-13       Impact factor: 5.157

9.  Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E.

Authors:  D Engelkamp; B W Schäfer; M G Mattei; P Erne; C W Heizmann
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-15       Impact factor: 11.205

Review 10.  S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles.

Authors:  R Donato
Journal:  Int J Biochem Cell Biol       Date:  2001-07       Impact factor: 5.085
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  27 in total

1.  Targeting Triple Negative Breast Cancer with a Nucleus-Directed p53 Tetramerization Domain Peptide.

Authors:  Gu Xiao; George K Annor; Kimberly Fung; Outi Keinänen; Brian M Zeglis; Jill Bargonetti
Journal:  Mol Pharm       Date:  2020-12-08       Impact factor: 4.939

2.  Crystallization and calcium/sulfur SAD phasing of the human EF-hand protein S100A2.

Authors:  Michael Koch; Joachim Diez; Armin Wagner; Günter Fritz
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-08-26

Review 3.  S100A6 protein: functional roles.

Authors:  Rosario Donato; Guglielmo Sorci; Ileana Giambanco
Journal:  Cell Mol Life Sci       Date:  2017-04-17       Impact factor: 9.261

Review 4.  The tumor suppressor p53: from structures to drug discovery.

Authors:  Andreas C Joerger; Alan R Fersht
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-02-10       Impact factor: 10.005

5.  Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers.

Authors:  Jan van Dieck; Maria R Fernandez-Fernandez; Dmitry B Veprintsev; Alan R Fersht
Journal:  J Biol Chem       Date:  2009-03-18       Impact factor: 5.157

6.  Large-scale proteomic identification of S100 proteins in breast cancer tissues.

Authors:  Patrizia Cancemi; Gianluca Di Cara; Nadia Ninfa Albanese; Francesca Costantini; Maria Rita Marabeti; Rosa Musso; Carmelo Lupo; Elena Roz; Ida Pucci-Minafra
Journal:  BMC Cancer       Date:  2010-09-03       Impact factor: 4.430

7.  Clinical omics analysis of colorectal cancer incorporating copy number aberrations and gene expression data.

Authors:  Tsuyoshi Yoshida; Takumi Kobayashi; Masaya Itoda; Taika Muto; Ken Miyaguchi; Kaoru Mogushi; Satoshi Shoji; Kazuro Shimokawa; Satoru Iida; Hiroyuki Uetake; Toshiaki Ishikawa; Kenichi Sugihara; Hiroshi Mizushima; Hiroshi Tanaka
Journal:  Cancer Inform       Date:  2010-07-29

8.  Thermodynamic and kinetic analysis of peptides derived from CapZ, NDR, p53, HDM2, and HDM4 binding to human S100B.

Authors:  Lucas N Wafer; Werner W Streicher; Scott A McCallum; George I Makhatadze
Journal:  Biochemistry       Date:  2012-08-29       Impact factor: 3.162

9.  Novel interactions of the TRTK12 peptide with S100 protein family members: specificity and thermodynamic characterization.

Authors:  Lucas N Wafer; Franco O Tzul; Pranav P Pandharipande; George I Makhatadze
Journal:  Biochemistry       Date:  2013-08-15       Impact factor: 3.162

10.  Structural and thermodynamic characterization of the recognition of the S100-binding peptides TRTK12 and p53 by calmodulin.

Authors:  Lucas N Wafer; Franco O Tzul; Pranav P Pandharipande; Scott A McCallum; George I Makhatadze
Journal:  Protein Sci       Date:  2014-07-02       Impact factor: 6.725
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