| Literature DB >> 18691608 |
Amir R R Kermany1, Xiaowen Zhou, Donal A Hickey.
Abstract
An expression for joint stationary moments of a diffusion approximation to a generalized Wright-Fisher model, corresponding to two finite populations of equal sizes, with migration and mutation, is derived. This gives a complete description of the stationary distribution of allele frequencies in the balance between migration, mutation and genetic drift. We derive the sampling formula in terms of the joint stationary moments, and we also prove that the diffusion process corresponding to this model of population division is not reversible.Mesh:
Year: 2008 PMID: 18691608 DOI: 10.1016/j.tpb.2008.07.004
Source DB: PubMed Journal: Theor Popul Biol ISSN: 0040-5809 Impact factor: 1.570