Literature DB >> 186775

DNA gyrase: an enzyme that introduces superhelical turns into DNA.

M Gellert, K Mizuuchi, M H O'Dea, H A Nash.   

Abstract

Relaxed closed-circular DNA is converted to negatively supercoiled DNA by DNA gyrase. This enzyme has been purified from Escherichia coli cells. The reaction requires ATP and Mg++ and is stimulated by spermidine. The enzyme acts equally well on relaxed closed-circular colicin E1, phage lambda, and simian virus 40 DNA. The final superhelix density of the DNA can be considerably greater than that found in intracellularly supercoiled DNA.

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Year:  1976        PMID： 186775      PMCID： PMC431247          DOI： 10.1073/pnas.73.11.3872

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  16 in total

1.  Letters to the editor: Novobiocin-a specific inhibitor of semiconservative DNA replication in permeabilized Escherichia coli cells.

Authors:  W L Staudenbauer
Journal:  J Mol Biol       Date:  1975-07-25       Impact factor: 5.469

2.  Restriction assay for integrative recombination of bacteriophage lambda DNA in vitro: requirement for closed circular DNA substrate.

Authors:  K Mizuuchi; H A Nash
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

3.  Characterization of purified DNA-relaxing enzyme from human tissue culture cells.

Authors:  W Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1975-07       Impact factor: 11.205

4.  Deoxyribonucleic acid plymerase II. of Escherichia coli. I. The purification and characterization of the enzyme.

Authors:  R B Wickner; B Ginsberg; I Berkower; J Hurwitz
Journal:  J Biol Chem       Date:  1972-01-25       Impact factor: 5.157

5.  An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

Authors:  J J Champoux; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

6.  Interaction of closed circular DNA with intercalative dyes. II. The free energy of superhelix formation in SV40 DNA.

Authors:  W Bauer; J Vinograd
Journal:  J Mol Biol       Date:  1970-02-14       Impact factor: 5.469

7.  A procedure for the rapid, large-scall purification of Escherichia coli DNA-dependent RNA polymerase involving Polymin P precipitation and DNA-cellulose chromatography.

Authors:  R R Burgess; J J Jendrisak
Journal:  Biochemistry       Date:  1975-10-21       Impact factor: 3.162

8.  Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

Authors:  W Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

9.  Structure of replicating simian virus 40 deoxyribonucleic acid molecules.

Authors:  E D Sebring; T J Kelly; M M Thoren; N P Salzman
Journal:  J Virol       Date:  1971-10       Impact factor: 5.103

10.  Integrative recombination of bacteriophage lambda DNA in vitro.

Authors:  H A Nash
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205
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  434 in total

1.  Transcription-dependent R-loop formation at mammalian class switch sequences.

Authors:  R B Tracy; M R Lieber
Journal:  EMBO J       Date:  2000-03-01       Impact factor: 11.598

2.  Construction and characterization of mutations at codon 751 of the Escherichia coli gyrB gene that confer resistance to the antimicrobial peptide microcin B17 and alter the activity of DNA gyrase.

Authors:  F J del Castillo; I del Castillo; F Moreno
Journal:  J Bacteriol       Date:  2001-03       Impact factor: 3.490

3.  GyrI: a counter-defensive strategy against proteinaceous inhibitors of DNA gyrase.

Authors:  Monalisa Chatterji; Valakunja Nagaraja
Journal:  EMBO Rep       Date:  2002-02-15       Impact factor: 8.807

4.  Type I topoisomerase activity is required for proper chromosomal segregation in Escherichia coli.

Authors:  Q Zhu; P Pongpech; R J DiGate
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-07       Impact factor: 11.205

5.  Equilibrium distributions of topological states in circular DNA: interplay of supercoiling and knotting.

Authors:  A A Podtelezhnikov; N R Cozzarelli; A V Vologodskii
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-09       Impact factor: 11.205

6.  Impact of gyrA and parC mutations on quinolone resistance, doubling time, and supercoiling degree of Escherichia coli.

Authors:  S Bagel; V Hüllen; B Wiedemann; P Heisig
Journal:  Antimicrob Agents Chemother       Date:  1999-04       Impact factor: 5.191

7.  Alteration of Escherichia coli topoisomerase IV to novobiocin resistance.

Authors:  Christine D Hardy; Nicholas R Cozzarelli
Journal:  Antimicrob Agents Chemother       Date:  2003-03       Impact factor: 5.191

8.  Streptococcus pneumoniae DNA gyrase and topoisomerase IV: overexpression, purification, and differential inhibition by fluoroquinolones.

Authors:  X S Pan; L M Fisher
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

9.  Gyrase inhibitors can increase gyrA expression and DNA supercoiling.

Authors:  R J Franco; K Drlica
Journal:  J Bacteriol       Date:  1989-12       Impact factor: 3.490

10.  DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis.

Authors:  A N Samadpour; H Merrikh
Journal:  Mol Microbiol       Date:  2018-03-06       Impact factor: 3.501
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