PURPOSE: To determine the demographic factors associated with central corneal thickness (CCT) in Northwestern American Indians/Alaskan Natives (AI/ANs) and to compare these CCT measurements with those of White and African-American persons. DESIGN: Cross-sectional comparative, observational study. METHODS: We performed ultrasonic pachymetry (DGH-500 Pachette; DGH Technologies, Exton, Pennsylvania, USA) on a random sample of AI/AN subjects from three randomly selected AI/AN tribes in the Northwest United States (n = 429). Pachymetry also was performed on a convenience sample of White (n = 46) and African-American (n = 33) persons. Our main outcome measure was the average of right and left eye CCT. RESULTS: Average AI/AN CCT was 554.8 +/- 33.9 microm. AI/AN CCT was found to be thicker than that of African Americans (528.5 +/- 33.2 microm) but similar to that of White persons (551.9 +/- 28.3 microm). CCT was greater in AI/AN females than in AI/AN males (557.6 +/- 33.3 microm vs 550.1 +/- 34.5 microm; P = .03). We found no difference in CCT based on percent AI/AN heritage, age, and keratometry readings. We found no significant differences in mean CCT between AI/ANs with glaucoma (556.2 microm) and those who did not have glaucoma (556.6 microm). CONCLUSIONS: CCT measurements for the Northwest AI/AN population are similar to those of White persons but thicker than those of African-American persons. Although glaucoma is common in AI/ANs, we did not find an association with thin CCT. We need future studies to explore the risk factors for glaucoma in AI/ANs.
PURPOSE: To determine the demographic factors associated with central corneal thickness (CCT) in Northwestern American Indians/Alaskan Natives (AI/ANs) and to compare these CCT measurements with those of White and African-American persons. DESIGN: Cross-sectional comparative, observational study. METHODS: We performed ultrasonic pachymetry (DGH-500 Pachette; DGH Technologies, Exton, Pennsylvania, USA) on a random sample of AI/AN subjects from three randomly selected AI/AN tribes in the Northwest United States (n = 429). Pachymetry also was performed on a convenience sample of White (n = 46) and African-American (n = 33) persons. Our main outcome measure was the average of right and left eye CCT. RESULTS: Average AI/AN CCT was 554.8 +/- 33.9 microm. AI/AN CCT was found to be thicker than that of African Americans (528.5 +/- 33.2 microm) but similar to that of White persons (551.9 +/- 28.3 microm). CCT was greater in AI/AN females than in AI/AN males (557.6 +/- 33.3 microm vs 550.1 +/- 34.5 microm; P = .03). We found no difference in CCT based on percent AI/AN heritage, age, and keratometry readings. We found no significant differences in mean CCT between AI/ANs with glaucoma (556.2 microm) and those who did not have glaucoma (556.6 microm). CONCLUSIONS: CCT measurements for the Northwest AI/AN population are similar to those of White persons but thicker than those of African-American persons. Although glaucoma is common in AI/ANs, we did not find an association with thin CCT. We need future studies to explore the risk factors for glaucoma in AI/ANs.
Authors: Steven L Mansberger; Francine C Romero; Nicole H Smith; Chris A Johnson; George A Cioffi; Beth Edmunds; Dongseok Choi; Thomas M Becker Journal: Am J Public Health Date: 2005-05 Impact factor: 9.308
Authors: Mauro T Leite; Luciana M Alencar; Charlotte Gore; Robert N Weinreb; Pamela A Sample; Linda M Zangwill; Felipe A Medeiros Journal: Am J Ophthalmol Date: 2010-06-11 Impact factor: 5.258
Authors: Xiaoyi Gao; W James Gauderman; Yutao Liu; Paul Marjoram; Mina Torres; Talin Haritunians; Jane Z Kuo; Yii-Der I Chen; R Rand Allingham; Michael A Hauser; Kent D Taylor; Jerome I Rotter; Rohit Varma Journal: Invest Ophthalmol Vis Sci Date: 2013-04-01 Impact factor: 4.799