Literature DB >> 18670440

The paradox of model organisms. The use of model organisms in research will continue despite their shortcomings.

Philip Hunter.   

Abstract

Mesh:

Year:  2008        PMID: 18670440      PMCID: PMC2515201          DOI: 10.1038/embor.2008.142

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


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  10 in total

1.  Cell biology. Whither model organism research?

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Journal:  Science       Date:  2005-03-25       Impact factor: 47.728

2.  British rethinking test rules after drug trial nearly kills 6.

Authors:  Elisabeth Rosenthal
Journal:  N Y Times Web       Date:  2006-04-08

3.  Physiologic and aberrant regulation of memory T-cell trafficking by the costimulatory molecule CD28.

Authors:  Vincenzo Mirenda; Sarah J Jarmin; Rachel David; Julian Dyson; Diane Scott; Yan Gu; Robert I Lechler; Klaus Okkenhaug; Federica M Marelli-Berg
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4.  The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprinting.

Authors:  Claudia Köhler; Damian R Page; Valeria Gagliardini; Ueli Grossniklaus
Journal:  Nat Genet       Date:  2004-12-26       Impact factor: 38.330

5.  The ethics of animal research. Talking Point on the use of animals in scientific research.

Authors:  Simon Festing; Robin Wilkinson
Journal:  EMBO Rep       Date:  2007-06       Impact factor: 8.807

6.  Animal research: a moral science. Talking Point on the use of animals in scientific research.

Authors:  Bernard E Rollin
Journal:  EMBO Rep       Date:  2007-06       Impact factor: 8.807

Review 7.  Gli proteins and Hedgehog signaling: development and cancer.

Authors:  A Ruiz i Altaba
Journal:  Trends Genet       Date:  1999-10       Impact factor: 11.639

Review 8.  The impact of developmental biology on cancer research: an overview.

Authors:  P A Edwards
Journal:  Cancer Metastasis Rev       Date:  1999       Impact factor: 9.264

9.  Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.

Authors:  A Donovan; A Brownlie; Y Zhou; J Shepard; S J Pratt; J Moynihan; B H Paw; A Drejer; B Barut; A Zapata; T C Law; C Brugnara; S E Lux; G S Pinkus; J L Pinkus; P D Kingsley; J Palis; M D Fleming; N C Andrews; L I Zon
Journal:  Nature       Date:  2000-02-17       Impact factor: 49.962

10.  CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila.

Authors:  J C Yin; M Del Vecchio; H Zhou; T Tully
Journal:  Cell       Date:  1995-04-07       Impact factor: 41.582

  10 in total
  18 in total

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2.  Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts.

Authors:  Gabriel Sturm; Andres Cardenas; Marie-Abèle Bind; Steve Horvath; Shuang Wang; Yunzhang Wang; Sara Hägg; Michio Hirano; Martin Picard
Journal:  Epigenetics       Date:  2019-06-12       Impact factor: 4.528

3.  Molecular characterization of the human ovulatory cascade-lesson from the IVF/IVM model.

Authors:  Gil M Yerushalmi; Ettie Maman; Yuval Yung; Alon Kedem; Ariel Hourvitz
Journal:  J Assist Reprod Genet       Date:  2011-06-11       Impact factor: 3.412

4.  Faraway, so close. The comparative method and the potential of non-model animals in mitochondrial research.

Authors:  Liliana Milani; Fabrizio Ghiselli
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-12-02       Impact factor: 6.237

Review 5.  'Fly-ing' from rare to common neurodegenerative disease mechanisms.

Authors:  Mengqi Ma; Matthew J Moulton; Shenzhao Lu; Hugo J Bellen
Journal:  Trends Genet       Date:  2022-04-25       Impact factor: 11.821

6.  A novel electronic assessment strategy to support applied Drosophila genetics training in university courses.

Authors:  Maggy Fostier; Sanjai Patel; Samantha Clarke; Andreas Prokop
Journal:  G3 (Bethesda)       Date:  2015-02-25       Impact factor: 3.154

7.  Tissue-specific direct microtransfer of nanomaterials into Drosophila embryos as a versatile in vivo test bed for nanomaterial toxicity assessment.

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Journal:  Int J Nanomedicine       Date:  2014-04-22

8.  Genome-wide patterns of polymorphism in an inbred line of the African malaria mosquito Anopheles gambiae.

Authors:  David A Turissini; Stephanie Gamez; Bradley J White
Journal:  Genome Biol Evol       Date:  2014-11-05       Impact factor: 3.416

9.  Forward Genetics by Sequencing EMS Variation-Induced Inbred Lines.

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Journal:  G3 (Bethesda)       Date:  2017-02-09       Impact factor: 3.154

Review 10.  Human carboxylesterases and fluorescent probes to image their activity in live cells.

Authors:  Anchal Singh; Mingze Gao; Michael W Beck
Journal:  RSC Med Chem       Date:  2021-05-18
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