Literature DB >> 18669449

Challenges and pitfalls of combining targeted agents in phase I studies.

Stephen A Cannistra.   

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Year:  2008        PMID: 18669449     DOI: 10.1200/JCO.2008.17.2676

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN: 0732-183X            Impact factor:   44.544


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  15 in total

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Review 2.  Envisioning the future of early anticancer drug development.

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4.  Bevacizumab in ovarian cancer: unanswered questions.

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Journal:  Drugs       Date:  2012-05-07       Impact factor: 9.546

5.  A Phase I/II adaptive design to determine the optimal treatment regimen from a set of combination immunotherapies in high-risk melanoma.

Authors:  Nolan A Wages; Craig L Slingluff; Gina R Petroni
Journal:  Contemp Clin Trials       Date:  2015-01-29       Impact factor: 2.226

6.  Dose-finding designs for trials of molecularly targeted agents and immunotherapies.

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Review 7.  Targeting angiogenesis: progress with anti-VEGF treatment with large molecules.

Authors:  Axel Grothey; Evanthia Galanis
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8.  Modeling NSCLC progression: recent advances and opportunities available.

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Journal:  AAPS J       Date:  2013-02-13       Impact factor: 4.009

9.  Pharmacokinetic/Pharmacodynamic modeling of abexinostat-induced thrombocytopenia across different patient populations: application for the determination of the maximum tolerated doses in both lymphoma and solid tumour patients.

Authors:  Quentin Chalret du Rieu; Sylvain Fouliard; Mélanie White-Koning; Ioana Kloos; Etienne Chatelut; Marylore Chenel
Journal:  Invest New Drugs       Date:  2014-05-31       Impact factor: 3.850

10.  Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter?

Authors:  S Postel-Vinay; H-T Arkenau; D Olmos; J Ang; J Barriuso; S Ashley; U Banerji; J De-Bono; I Judson; S Kaye
Journal:  Br J Cancer       Date:  2009-05-05       Impact factor: 7.640

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