Literature DB >> 6714791

Neurotensin induced inhibition of gastric acid secretion in duodenal ulcer patients before and after parietal cell vagotomy.

P S Olsen, J H Pedersen, P Kirkegaard, H Been, F Stadil, J Fahrenkrug, J Christiansen.   

Abstract

The influence of the vagal nerve on the inhibitory effect of neurotensin on pentagastrin stimulated gastric acid secretion was investigated in seven duodenal ulcer patients before and after parietal cell vagotomy without drainage. Preoperatively, neurotensin inhibited gastric acid secretion, whereas no effect was found postoperatively. Plasma concentration of neurotensin was identical pre-and postoperatively. This study shows that the inhibitory effect of neurotensin on gastric acid secretion is dependent on an intact vagal innervation of the parietal cell area.

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Year:  1984        PMID： 6714791      PMCID： PMC1432443          DOI： 10.1136/gut.25.5.481

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  16 in total

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Authors:  J H BARON
Journal:  Clin Sci       Date:  1963-06       Impact factor: 6.124

2.  Theoretical considerations concerning gastric inhibition.

Authors:  K J Obrink
Journal:  Scand J Gastroenterol Suppl       Date:  1976

3.  Specific localisation of neurotensin to the N cell in human intestine by radioimmunoassay and immunocytochemistry.

Authors:  J M Polak; S N Sullivan; S R Bloom; A M Buchan; P Facer; M R Brown; A G Pearse
Journal:  Nature       Date:  1977-11-10       Impact factor: 49.962

4.  Preparation of 125I-(Tyr 3)- and 125I-(Tyr 11)- neurotensin for radioimmunoassay.

Authors:  J H Pedersen; F Stadil; J Fahrenkrug
Journal:  Scand J Clin Lab Invest       Date:  1983-10       Impact factor: 1.713

5.  Tissue localization and relative distribution of regulatory peptides in separated layers from the human bowel.

Authors:  G L Ferri; T E Adrian; M A Ghatei; D J O'Shaughnessy; L Probert; Y C Lee; A M Buchan; J M Polak; S R Bloom
Journal:  Gastroenterology       Date:  1983-04       Impact factor: 22.682

6.  Inhibition of gastric acid secretion in man by exogenous and endogenous pancreatic glucagon.

Authors:  J Christiansen; J J Holst; E Kalaja
Journal:  Gastroenterology       Date:  1976-05       Impact factor: 22.682

7.  Neurotensin inhibits meal-stimulated gastric acid secretion in man.

Authors:  P Skov Olsen; J Holst Pedersen; P Kirkegaard; F Stadil; J Fahrenkrug; J Christiansen
Journal:  Scand J Gastroenterol       Date:  1983-11       Impact factor: 2.423

8.  Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach.

Authors:  R Carraway; S E Leeman
Journal:  J Biol Chem       Date:  1976-11-25       Impact factor: 5.157

9.  Prospective controlled vagotomy trial for duodenal ulcer: primary results, sequelae, acid secretion, and recurrence rates two to five years after operation.

Authors:  J Christiansen; H E Jensen; P Ejby-Poulsen; L Bardram; F W Henriksen
Journal:  Ann Surg       Date:  1981-01       Impact factor: 12.969

10.  Fat inhibition of gastric acid secretion in man and plasma concentrations of neurotensin-like immunoreactivity.

Authors:  B Kihl; A Rökaeus; S Rosell; L Olbe
Journal:  Scand J Gastroenterol       Date:  1981       Impact factor: 2.423
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  6 in total

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Authors:  F P Brooks
Journal:  Dig Dis Sci       Date:  1985-11       Impact factor: 3.199

3.  Regulation of gastric acid secretion by neurotensin in man. Evidence against a hormonal role.

Authors:  M H Mogard; V Maxwell; B Sytnik; J H Walsh
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4.  Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.

Authors:  A Wettergren; B Schjoldager; P E Mortensen; J Myhre; J Christiansen; J J Holst
Journal:  Dig Dis Sci       Date:  1993-04       Impact factor: 3.199

5.  Effect of proximal gastric vagotomy on calculated gastric HCO3- and nonparietal volume secretion in man. Studies during basal conditions and gastrin-17 infusion.

Authors:  M Feldman; A J Blair; C T Richardson
Journal:  J Clin Invest       Date:  1987-06       Impact factor: 14.808

6.  Ileal release of glucagon-like peptide-1 (GLP-1). Association with inhibition of gastric acid secretion in humans.

Authors:  P Layer; J J Holst; D Grandt; H Goebell
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  6 in total

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