Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Revised structure of deacetyl-1,10-didehydrosalvinorin G.

Literature DB >> 18665199

Revised structure of deacetyl-1,10-didehydrosalvinorin G.

Abstract

In comparison with the NMR data of salvinorin A and its 8-epimer, the published structure of deacetyl-1,10-didehydrosalvinorin G was revised to its 8-epimer. The stereochemistry of 8-epi-deacetyl-1,10-didehydrosalvinorin G was further confirmed by NOESY and chemical synthesis.

Entities: Chemical

Year: 2007 PMID： 18665199 PMCID： PMC2390872 DOI： 10.1016/j.tetlet.2007.05.179

Source DB: PubMed Journal: Tetrahedron Lett ISSN： 0040-4039 Impact factor: 2.415

20 in total

1. Synthesis and in vitro pharmacological studies of new C(4)-modified salvinorin A analogues.

Authors: David Y W Lee; Minsheng He; Lee-Yuan Liu-Chen; Yulin Wang; Jian-Guo Li; Wei Xu; Zhongze Ma; William A Carlezon; Bruce Cohen
Journal: Bioorg Med Chem Lett Date: 2006-08-30 Impact factor: 2.823

2. Synthesis of salvinorin A analogues as opioid receptor probes.

Authors: Kevin Tidgewell; Wayne W Harding; Anthony Lozama; Howard Cobb; Kushal Shah; Pavitra Kannan; Christina M Dersch; Damon Parrish; Jeffrey R Deschamps; Richard B Rothman; Thomas E Prisinzano
Journal: J Nat Prod Date: 2006-06 Impact factor: 4.050

3. Autoxidation of salvinorin A under basic conditions.

Authors: Thomas A Munro; Glenn W Goetchius; Bryan L Roth; Timothy A Vortherms; Mark A Rizzacasa
Journal: J Org Chem Date: 2005-11-25 Impact factor: 4.354

4. New neoclerodane diterpenoids isolated from the leaves of Salvia divinorum and their binding affinities for human kappa opioid receptors.

Authors: David Y W Lee; Zhongze Ma; Lee-Yuan Liu-Chen; Yulin Wang; Yong Chen; William A Carlezon; Bruce Cohen
Journal: Bioorg Med Chem Date: 2005-10-01 Impact factor: 3.641

5. Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist.

Authors: Thomas A Munro; Mark A Rizzacasa; Bryan L Roth; Beth A Toth; Feng Yan
Journal: J Med Chem Date: 2005-01-27 Impact factor: 7.446

6. Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum.

Authors: L J Valdés; H M Chang; D C Visger; M Koreeda
Journal: Org Lett Date: 2001-11-29 Impact factor: 6.005

7. Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues.

Authors: David Y W Lee; Minsheng He; Leelakrishna Kondaveti; Lee-Yuan Liu-Chen; Zhongze Ma; Yulin Wang; Yong Chen; Jian-Guo Li; Cecile Beguin; William A Carlezon; Bruce Cohen
Journal: Bioorg Med Chem Lett Date: 2005-10-01 Impact factor: 2.823

8. Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

Authors: Wayne W Harding; Kevin Tidgewell; Nathan Byrd; Howard Cobb; Christina M Dersch; Eduardo R Butelman; Richard B Rothman; Thomas E Prisinzano
Journal: J Med Chem Date: 2005-07-28 Impact factor: 7.446

9. Salvinorins D-F, new neoclerodane diterpenoids from Salvia divinorum, and an improved method for the isolation of salvinorin A.

Authors: Thomas A Munro; Mark A Rizzacasa
Journal: J Nat Prod Date: 2003-05 Impact factor: 4.050

10. Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations.

Authors: Charles Chavkin; Sumit Sud; Wenzhen Jin; Jeremy Stewart; Jordan K Zjawiony; Daniel J Siebert; Beth Ann Toth; Sandra J Hufeisen; Bryan L Roth
Journal: J Pharmacol Exp Ther Date: 2004-01-08 Impact factor: 4.030

8 in total

Review 8. Natural Products for the Treatment of Pain: Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide.

Authors: Soumen Chakraborty; Susruta Majumdar
Journal: Biochemistry Date: 2020-09-22 Impact factor: 3.162

8 in total

Revised structure of deacetyl-1,10-didehydrosalvinorin G.

1. Synthesis and in vitro pharmacological studies of new C(4)-modified salvinorin A analogues.

2. Synthesis of salvinorin A analogues as opioid receptor probes.

3. Autoxidation of salvinorin A under basic conditions.

4. New neoclerodane diterpenoids isolated from the leaves of Salvia divinorum and their binding affinities for human kappa opioid receptors.

5. Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist.

6. Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum.

7. Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues.

8. Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

9. Salvinorins D-F, new neoclerodane diterpenoids from Salvia divinorum, and an improved method for the isolation of salvinorin A.

10. Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations.

Review 1. Clerodane diterpenes: sources, structures, and biological activities.

Review 2. Salvinorin A analogs as probes in opioid pharmacology.

Review 3. Neoclerodanes as atypical opioid receptor ligands.

Review 4. Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A.

5. Novel neoclerodane diterpene derivatives from the smoke of salvinorin A.

6. Synthesis of deacetyl-1,10-didehydrosalvinorin G.

Review 7. Natural products as tools for neuroscience: discovery and development of novel agents to treat drug abuse.

Review 8. Natural Products for the Treatment of Pain: Chemistry and Pharmacology of Salvinorin A, Mitragynine, and Collybolide.