Literature DB >> 18651282

Intraluminal thrombus and risk of rupture in patient specific abdominal aortic aneurysm - FSI modelling.

Danny Bluestein1, Kris Dumont, Matthieu De Beule, John Ricotta, Paul Impellizzeri, Benedict Verhegghe, Pascal Verdonck.   

Abstract

Recent numerical studies of abdominal aortic aneurysm (AAA) suggest that intraluminal thrombus (ILT) may reduce the stress loading on the aneurysmal wall. Detailed fluid structure interaction (FSI) in the presence and absence of ILT may help predict AAA rupture risk better. Two patients, with varied AAA geometries and ILT structures, were studied and compared in detail. The patient specific 3D geometries were reconstructed from CT scans, and uncoupled FSI approach was applied. Complex flow trajectories within the AAA lumen indicated a viable mechanism for the formation and growth of the ILT. The resulting magnitude and location of the peak wall stresses was dependent on the shape of the AAA, and the ILT appeared to reduce wall stresses for both patients. Accordingly, the inclusion of ILT in stress analysis of AAA is of importance and would likely increase the accuracy of predicting AAA risk of rupture.

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Year:  2009        PMID: 18651282     DOI: 10.1080/10255840903077170

Source DB:  PubMed          Journal:  Comput Methods Biomech Biomed Engin        ISSN: 1025-5842            Impact factor:   1.763


  16 in total

1.  Association of Intraluminal Thrombus, Hemodynamic Forces, and Abdominal Aortic Aneurysm Expansion Using Longitudinal CT Images.

Authors:  Byron A Zambrano; Hamidreza Gharahi; ChaeYoung Lim; Farhad A Jaberi; Jongeun Choi; Whal Lee; Seungik Baek
Journal:  Ann Biomed Eng       Date:  2015-10-01       Impact factor: 3.934

2.  Flow interactions with cells and tissues: cardiovascular flows and fluid-structure interactions. Sixth International Bio-Fluid Mechanics Symposium and Workshop, March 28-30, 2008, Pasadena, California.

Authors:  Morton H Friedman; Rob Krams; Krishnan B Chandran
Journal:  Ann Biomed Eng       Date:  2010-03       Impact factor: 3.934

3.  Fluid-structure interaction modeling of abdominal aortic aneurysms: the impact of patient-specific inflow conditions and fluid/solid coupling.

Authors:  Santanu Chandra; Samarth S Raut; Anirban Jana; Robert W Biederman; Mark Doyle; Satish C Muluk; Ender A Finol
Journal:  J Biomech Eng       Date:  2013-08       Impact factor: 2.097

4.  Investigation of material modeling in fluid-structure interaction analysis of an idealized three-layered abdominal aorta: aneurysm initiation and fully developed aneurysms.

Authors:  Fatma Gulden Simsek; Young W Kwon
Journal:  J Biol Phys       Date:  2015-01-27       Impact factor: 1.365

5.  A Methodology for the Derivation of Unloaded Abdominal Aortic Aneurysm Geometry With Experimental Validation.

Authors:  Santanu Chandra; Vimalatharmaiyah Gnanaruban; Fabian Riveros; Jose F Rodriguez; Ender A Finol
Journal:  J Biomech Eng       Date:  2016-10-01       Impact factor: 2.097

6.  Progression of abdominal aortic aneurysm towards rupture: refining clinical risk assessment using a fully coupled fluid-structure interaction method.

Authors:  Michalis Xenos; Nicos Labropoulos; Suraj Rambhia; Yared Alemu; Shmuel Einav; Apostolos Tassiopoulos; Natzi Sakalihasan; Danny Bluestein
Journal:  Ann Biomed Eng       Date:  2014-12-20       Impact factor: 3.934

7.  The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries.

Authors:  Michalis Xenos; Yared Alemu; Dan Zamfir; Shmuel Einav; John J Ricotta; Nicos Labropoulos; Apostolos Tassiopoulos; Danny Bluestein
Journal:  Med Biol Eng Comput       Date:  2010-11-19       Impact factor: 2.602

8.  Chiropractic Management of a Patient With Thoracic Pain and a Stable Thoracic Aortic Aneurysm: A Case Report.

Authors:  Shawn M Neff; Casey S Okamoto
Journal:  J Chiropr Med       Date:  2016-12-06

9.  Interaction of expanding abdominal aortic aneurysm with surrounding tissue: Retrospective CT image studies.

Authors:  Sebastian T Kwon; William Burek; Alexander C Dupay; Mehdi Farsad; Seungik Baek; Eun-Ah Park; Whal Lee
Journal:  J Nat Sci       Date:  2015-08

Review 10.  Cardiovascular disease management: the need for better diagnostics.

Authors:  John J Ricotta; Jose Pagan; Michalis Xenos; Yared Alemu; Shmuel Einav; Danny Bluestein
Journal:  Med Biol Eng Comput       Date:  2008-11-11       Impact factor: 2.602

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