Literature DB >> 1864597

Prospects for homologous recombination in human gene therapy.

M A Vega1.   

Abstract

The ideal approach to gene therapy of hereditary diseases or gene correction therapy is considered. The advantages, disadvantages and limits of gene targeting by homologous recombination are discussed with regard to its possible application in gene correction therapy and in comparison with retroviral-mediated gene complementation therapy.

Entities:  

Mesh：

Year:  1991        PMID： 1864597     DOI： 10.1007/bf00200899

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  86 in total

1.  Site-specific gene expression in vivo by direct gene transfer into the arterial wall.

Authors:  E G Nabel; G Plautz; G J Nabel
Journal:  Science       Date:  1990-09-14       Impact factor: 47.728

2.  Expression of human class II major histocompatibility complex antigens using retrovirus vectors.

Authors:  A J Korman; J D Frantz; J L Strominger; R C Mulligan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

3.  Mechanisms of nonhomologous recombination in mammalian cells.

Authors:  D B Roth; T N Porter; J H Wilson
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

4.  Homologous recombination in hybridoma cells: heavy chain chimeric antibody produced by gene targeting.

Authors:  H P Fell; S Yarnold; I Hellström; K E Hellström; K R Folger
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

5.  Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene.

Authors:  K R Thomas; M R Capecchi
Journal:  Nature       Date:  1986 Nov 6-12       Impact factor: 49.962

Review 6.  Research and potential clinical applications of retroviral vectors.

Authors:  L A Donehower
Journal:  Prog Med Virol       Date:  1987

7.  Homologous recombination of SV40 DNA in COS7 cells occurs with high frequency in a gene dose independent fashion.

Authors:  W Rommerskirch; I Graeber; M Grässmann; A Grässmann
Journal:  Nucleic Acids Res       Date:  1988-02-11       Impact factor: 16.971

8.  Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes.

Authors:  S L Mansour; K R Thomas; M R Capecchi
Journal:  Nature       Date:  1988-11-24       Impact factor: 49.962

9.  Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions.

Authors:  K Mooslehner; U Karls; K Harbers
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

10.  Correction of CD18-deficient lymphocytes by retrovirus-mediated gene transfer.

Authors:  J M Wilson; A J Ping; J C Krauss; L Mayo-Bond; C E Rogers; D C Anderson; R F Todd
Journal:  Science       Date:  1990-06-15       Impact factor: 47.728
View more
  8 in total

1.  Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase.

Authors:  B Thyagarajan; E C Olivares; R P Hollis; D S Ginsburg; M P Calos
Journal:  Mol Cell Biol       Date:  2001-06       Impact factor: 4.272

2.  Site-specific integration of transgene targeting an endogenous lox-like site in early mouse embryos.

Authors:  Masanori Ito; Keitaro Yamanouchi; Kunihiko Naito; Michele P Calos; Hideaki Tojo
Journal:  J Appl Genet       Date:  2010-11-26       Impact factor: 3.240

3.  Processing of DNA prior to illegitimate recombination in mouse cells.

Authors:  G Henderson; J P Simons
Journal:  Mol Cell Biol       Date:  1997-07       Impact factor: 4.272

4.  A phage integrase directs efficient site-specific integration in human cells.

Authors:  A C Groth; E C Olivares; B Thyagarajan; M P Calos
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

5.  Gene targeting with a replication-defective adenovirus vector.

Authors:  A Fujita; K Sakagami; Y Kanegae; I Saito; I Kobayashi
Journal:  J Virol       Date:  1995-10       Impact factor: 5.103

Review 6.  Oligo/polynucleotide-based gene modification: strategies and therapeutic potential.

Authors:  R Geoffrey Sargent; Soya Kim; Dieter C Gruenert
Journal:  Oligonucleotides       Date:  2011-03-21

7.  DAXX interacts with phage PhiC31 integrase and inhibits recombination.

Authors:  Jin-zhong Chen; Chao-neng Ji; Guan-lan Xu; Rong-yan Pang; Ji-hua Yao; Huan-zhang Zhu; Jing-lun Xue; William Jia
Journal:  Nucleic Acids Res       Date:  2006-11-10       Impact factor: 16.971

Review 8.  The therapeutic potential of genome editing for β-thalassemia.

Authors:  Astrid Glaser; Bradley McColl; Jim Vadolas
Journal:  F1000Res       Date:  2015-12-11
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.