| Literature DB >> 18644250 |
Rushika Perera1, Richard J Kuhn.
Abstract
In this paper, we discuss recent advances in our knowledge of the dengue virus life cycle based on new structural data of the virus and its proteins. Specifically, we focus on the structure of the pre-membrane protein, prM and its role in virus assembly, the first full-length structure of a multi-domain dengue virus replication protein, NS3, and the recently solved structures of NS5 methyltransferase and polymerase domains. These structures provide a basis for describing function and predicting putative host interactions.Entities:
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Year: 2008 PMID： 18644250 PMCID： PMC2581888 DOI： 10.1016/j.mib.2008.06.004
Source DB: PubMed Journal: Curr Opin Microbiol ISSN： 1369-5274 Impact factor: 7.934