Literature DB >> 17301152

Rab 5 is required for the cellular entry of dengue and West Nile viruses.

Manoj N Krishnan1, Bindu Sukumaran, Utpal Pal, Herve Agaisse, James L Murray, Thomas W Hodge, Erol Fikrig.   

Abstract

The mechanisms of cellular entry of dengue and West Nile viruses are not well characterized. We show that both these viruses enter HeLa cells by clathrin-dependent endocytosis and require vacuolar acidic pH. Inhibition of the GTPase Rab 5 or 7, which regulates transport to early or late endosomes, respectively, demonstrated that Rab 5 was essential for survival of both dengue and West Nile virus. These data broaden our understanding of the pathways required for productive dengue and West Nile virus infection and may facilitate new strategies for combating disease.

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Year:  2007        PMID： 17301152      PMCID： PMC1900185          DOI： 10.1128/JVI.02210-06

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  25 in total

Review 1.  Rab proteins as membrane organizers.

Authors:  M Zerial; H McBride
Journal:  Nat Rev Mol Cell Biol       Date:  2001-02       Impact factor: 94.444

Review 2.  Endosomes: multipurpose designs for integrating housekeeping and specialized tasks.

Authors:  Martin Sachse; Georg Ramm; Ger Strous; Judith Klumperman
Journal:  Histochem Cell Biol       Date:  2001-12-14       Impact factor: 4.304

Review 3.  A journey from mammals to yeast with vacuolar H+-ATPase (V-ATPase).

Authors:  Nathan Nelson
Journal:  J Bioenerg Biomembr       Date:  2003-08       Impact factor: 2.945

4.  Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles.

Authors:  Laurent Meertens; Claire Bertaux; Tatjana Dragic
Journal:  J Virol       Date:  2006-09-27       Impact factor: 5.103

5.  Isolation of West Nile virus from mosquitoes, crows, and a Cooper's hawk in Connecticut.

Authors:  J F Anderson; T G Andreadis; C R Vossbrinck; S Tirrell; E M Wakem; R A French; A E Garmendia; H J Van Kruiningen
Journal:  Science       Date:  1999-12-17       Impact factor: 47.728

6.  Differential requirements of Rab5 and Rab7 for endocytosis of influenza and other enveloped viruses.

Authors:  Sara B Sieczkarski; Gary R Whittaker
Journal:  Traffic       Date:  2003-05       Impact factor: 6.215

Review 7.  The molecular biology of West Nile Virus: a new invader of the western hemisphere.

Authors:  Margo A Brinton
Journal:  Annu Rev Microbiol       Date:  2002-01-30       Impact factor: 15.500

8.  Infectious entry of West Nile virus occurs through a clathrin-mediated endocytic pathway.

Authors:  J J H Chu; M L Ng
Journal:  J Virol       Date:  2004-10       Impact factor: 5.103

9.  Cell fusion activities of Hantaan virus envelope glycoproteins.

Authors:  Michiko Ogino; Kumiko Yoshimatsu; Hideki Ebihara; Koichi Araki; Byoung-Hee Lee; Megumi Okumura; Jiro Arikawa
Journal:  J Virol       Date:  2004-10       Impact factor: 5.103

10.  Membrane fusion mutants of Semliki Forest virus.

Authors:  M C Kielian; S Keränen; L Kääriäinen; A Helenius
Journal:  J Cell Biol       Date:  1984-01       Impact factor: 10.539
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  94 in total

1.  Virus-induced Ca2+ influx extends survival of west nile virus-infected cells.

Authors:  Svetlana V Scherbik; Margo A Brinton
Journal:  J Virol       Date:  2010-06-10       Impact factor: 5.103

2.  Rabies virus co-localizes with early (Rab5) and late (Rab7) endosomal proteins in neuronal and SH-SY5Y cells.

Authors:  Waqas Ahmad; Yingying Li; Yidi Guo; Xinyu Wang; Ming Duan; Zhenhong Guan; Zengshan Liu; Maolin Zhang
Journal:  Virol Sin       Date:  2017-06-16       Impact factor: 4.327

Review 3.  Biochemistry and Molecular Biology of Flaviviruses.

Authors:  Nicholas J Barrows; Rafael K Campos; Kuo-Chieh Liao; K Reddisiva Prasanth; Ruben Soto-Acosta; Shih-Chia Yeh; Geraldine Schott-Lerner; Julien Pompon; October M Sessions; Shelton S Bradrick; Mariano A Garcia-Blanco
Journal:  Chem Rev       Date:  2018-04-13       Impact factor: 60.622

Review 4.  Molecular targets for flavivirus drug discovery.

Authors:  Aruna Sampath; R Padmanabhan
Journal:  Antiviral Res       Date:  2008-09-15       Impact factor: 5.970

Review 5.  Closing the door on flaviviruses: entry as a target for antiviral drug design.

Authors:  Rushika Perera; Mansoora Khaliq; Richard J Kuhn
Journal:  Antiviral Res       Date:  2008-06-11       Impact factor: 5.970

6.  Rab5 and Rab11 Are Required for Clathrin-Dependent Endocytosis of Japanese Encephalitis Virus in BHK-21 Cells.

Authors:  Chun-Chun Liu; Yun-Na Zhang; Zhao-Yao Li; Jin-Xiu Hou; Jing Zhou; Lin Kan; Bin Zhou; Pu-Yan Chen
Journal:  J Virol       Date:  2017-09-12       Impact factor: 5.103

7.  Protonation of individual histidine residues is not required for the pH-dependent entry of west nile virus: evaluation of the "histidine switch" hypothesis.

Authors:  Steevenson Nelson; Subhajit Poddar; Tsai-Yu Lin; Theodore C Pierson
Journal:  J Virol       Date:  2009-09-23       Impact factor: 5.103

8.  West Nile virus entry requires cholesterol-rich membrane microdomains and is independent of alphavbeta3 integrin.

Authors:  Guruprasad R Medigeshi; Alec J Hirsch; Daniel N Streblow; Janko Nikolich-Zugich; Jay A Nelson
Journal:  J Virol       Date:  2008-04-02       Impact factor: 5.103

9.  Regulation of hepatitis B virus infection by Rab5, Rab7, and the endolysosomal compartment.

Authors:  Alina Macovei; Catalina Petrareanu; Catalin Lazar; Paula Florian; Norica Branza-Nichita
Journal:  J Virol       Date:  2013-03-27       Impact factor: 5.103

10.  Involvement of ceramide in the propagation of Japanese encephalitis virus.

Authors:  Hideki Tani; Mai Shiokawa; Yuuki Kaname; Hiroto Kambara; Yoshio Mori; Takayuki Abe; Kohji Moriishi; Yoshiharu Matsuura
Journal:  J Virol       Date:  2010-01-06       Impact factor: 5.103
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