| Literature DB >> 1864207 |
A J Wakefield1, A M Sawyerr, M Hudson, A P Dhillon, R E Pounder.
Abstract
Both cigarette smoking and the oral contraceptive pill have been implicated as aggravating factors in Crohn's disease. Based upon the recent demonstration of multifocal gastrointestinal infarction in Crohn's disease, a possible pathogenic mechanism for this condition, we propose how smoking and the oral contraceptive pill may potentiate a tendency for focal thrombosis and hence exacerbate the activity of Crohn's disease.Entities:
Keywords: Behavior; Biology; Blood Coagulation Effects; Contraception; Contraceptive Methods--side effects; Family Planning; Gastrointestinal Effects--etiology; Hematological Effects; Hemic System; Oral Contraceptives--side effects; Physiology; Smoking--side effects
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Year: 1991 PMID: 1864207 DOI: 10.1007/bf01297463
Source DB: PubMed Journal: Dig Dis Sci ISSN: 0163-2116 Impact factor: 3.199