Literature DB >> 7781467

Severe thrombotic complications in a postpartum patient with active Crohn's disease resulting in ischemic spinal cord injury.

W B Slot1, V van Kasteel, E G Coerkamp, P J Seelen, S D van der Werf.   

Abstract

This report describes a 33-year-old female patient who presented with severe neurological symptoms and signs during postpartum relapse of Crohn's ileocolitis. The cause of the neurological deficit was extensive major vessel thrombosis resulting in spinal cord ischemia. Etiologic factors involved in this exceptional thrombotic state are discussed with emphasis on the relationship between low levels of folic acid, homocysteine metabolism, and coagulation.

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Year:  1995        PMID: 7781467     DOI: 10.1007/bf02065558

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  14 in total

Review 1.  Smoking, the oral contraceptive pill, and Crohn's disease.

Authors:  A J Wakefield; A M Sawyerr; M Hudson; A P Dhillon; R E Pounder
Journal:  Dig Dis Sci       Date:  1991-08       Impact factor: 3.199

2.  Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography-mass spectrometry.

Authors:  S P Stabler; P D Marcell; E R Podell; R H Allen; D G Savage; J Lindenbaum
Journal:  J Clin Invest       Date:  1988-02       Impact factor: 14.808

3.  Vascular complications of inflammatory bowel disease.

Authors:  R W Talbot; J Heppell; R R Dozois; R W Beart
Journal:  Mayo Clin Proc       Date:  1986-02       Impact factor: 7.616

4.  Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.

Authors:  G M Rodgers; W H Kane
Journal:  J Clin Invest       Date:  1986-06       Impact factor: 14.808

5.  Higher total plasma homocysteine in vitamin B12 deficiency than in heterozygosity for homocystinuria due to cystathionine beta-synthase deficiency.

Authors:  L Brattström; B Israelsson; F Lindgärde; B Hultberg
Journal:  Metabolism       Date:  1988-02       Impact factor: 8.694

6.  Activation of blood coagulation in Crohn's disease. Increased plasma fibrinopeptide A levels and enhanced generation of monocyte tissue factor activity.

Authors:  R L Edwards; J B Levine; R Green; M Duffy; E Mathews; W Brande; F R Rickles
Journal:  Gastroenterology       Date:  1987-02       Impact factor: 22.682

7.  Immunohistochemical study of tissue factor expression in normal intestine and idiopathic inflammatory bowel disease.

Authors:  L More; R Sim; M Hudson; A P Dhillon; R Pounder; A J Wakefield
Journal:  J Clin Pathol       Date:  1993-08       Impact factor: 3.411

8.  The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

Authors:  S H Mudd; F Skovby; H L Levy; K D Pettigrew; B Wilcken; R E Pyeritz; G Andria; G H Boers; I L Bromberg; R Cerone
Journal:  Am J Hum Genet       Date:  1985-01       Impact factor: 11.025

Review 9.  Mechanisms of thrombogenesis and accelerated atherogenesis in homocysteinaemia.

Authors:  D E Wilcken; N P Dudman
Journal:  Haemostasis       Date:  1989

10.  Homocysteinemia due to folate deficiency.

Authors:  S S Kang; P W Wong; M Norusis
Journal:  Metabolism       Date:  1987-05       Impact factor: 8.694

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  3 in total

1.  Hyperhomocysteinemia in ulcerative colitis is related to folate levels.

Authors:  Petros Zezos; Georgia Papaioannou; Nikolaos Nikolaidis; Themistoclis Vasiliadis; Olga Giouleme; Nikolaos Evgenidis
Journal:  World J Gastroenterol       Date:  2005-10-14       Impact factor: 5.742

Review 2.  Neurology and the gastrointestinal system.

Authors:  G D Perkin; I Murray-Lyon
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-09       Impact factor: 10.154

3.  Homocysteine, cysteine, and glutathione in human colonic mucosa: elevated levels of homocysteine in patients with inflammatory bowel disease.

Authors:  I Morgenstern; M T M Raijmakers; W H M Peters; H Hoensch; W Kirch
Journal:  Dig Dis Sci       Date:  2003-10       Impact factor: 3.199

  3 in total

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