M O Owolabi1, S Ugoya, T Platz. 1. Department of Medicine, University College Hospital, Ibadan, Nigeria. mayowaowolabi@yahoo.com
Abstract
BACKGROUND: Different workers have reported racial disparities in the distribution of risk factors for stroke and stroke subtype (ischemic vs hemorrhagic). No transcultural transnational studies have been conducted to confirm and relate these disparities to one another. Our objective was to identify differences in the distribution of risk factors for stroke and stroke subtypes among urban-dwelling stroke patients in Nigeria, a developing country, and Germany, an industrialized country. METHODS: Consecutive stroke patients in Ibadan (100) and Berlin (103) were studied. Their hospital records were screened to identify documented vascular risk factors and stroke subtype. RESULTS: The stroke patients in Ibadan were younger than those in Berlin (t = 4.940, P = 0.000). Hypertension was significantly more common in Ibadan while cigarette smoking, dyslipidemia, atherosclerosis, and cardiac factors were significantly more frequent in Berlin. Cerebral infarction was more common in Berlin (80%) than in Ibadan (63%). CONCLUSION: The risk factors associated with cerebral infarction were more frequent in Berlin. We suspect that racial disparity in risk factors for stroke may account for the difference in proportions of stroke subtype in black and white populations. Larger prospective community-based multinational multiracial studies are required to confirm these disparities and identify possible underlying genetic, dietary, and socio-economic factors.
BACKGROUND: Different workers have reported racial disparities in the distribution of risk factors for stroke and stroke subtype (ischemic vs hemorrhagic). No transcultural transnational studies have been conducted to confirm and relate these disparities to one another. Our objective was to identify differences in the distribution of risk factors for stroke and stroke subtypes among urban-dwelling strokepatients in Nigeria, a developing country, and Germany, an industrialized country. METHODS: Consecutive strokepatients in Ibadan (100) and Berlin (103) were studied. Their hospital records were screened to identify documented vascular risk factors and stroke subtype. RESULTS: The strokepatients in Ibadan were younger than those in Berlin (t = 4.940, P = 0.000). Hypertension was significantly more common in Ibadan while cigarette smoking, dyslipidemia, atherosclerosis, and cardiac factors were significantly more frequent in Berlin. Cerebral infarction was more common in Berlin (80%) than in Ibadan (63%). CONCLUSION: The risk factors associated with cerebral infarction were more frequent in Berlin. We suspect that racial disparity in risk factors for stroke may account for the difference in proportions of stroke subtype in black and white populations. Larger prospective community-based multinational multiracial studies are required to confirm these disparities and identify possible underlying genetic, dietary, and socio-economic factors.
Authors: Mayowa Owolabi; Fred Sarfo; Virginia J Howard; Marguerite R Irvin; Mulugeta Gebregziabher; Rufus Akinyemi; Aleena Bennett; Kevin Armstrong; Hemant K Tiwari; Albert Akpalu; Kolawole W Wahab; Lukman Owolabi; Bimbo Fawale; Morenikeji Komolafe; Reginald Obiako; Philip Adebayo; Jennifer M Manly; Godwin Ogbole; Ezinne Melikam; Ruth Laryea; Raelle Saulson; Carolyn Jenkins; Donna K Arnett; Daniel T Lackland; Bruce Ovbiagele; George Howard Journal: Stroke Date: 2017-04-07 Impact factor: 7.914
Authors: Albert Akpalu; Fred Stephen Sarfo; Bruce Ovbiagele; Rufus Akinyemi; Mulugeta Gebregziabher; Reginald Obiako; Lukman Owolabi; Kwamena Sagoe; Carolyn Jenkins; Oyedunni Arulogun; Sheila Adamu; Lambert T Appiah; Martin A Adadey; Francis Agyekum; Joseph A Quansah; Yaw B Mensah; Abiodun M Adeoye; Arti Singh; Aridegbe O Tosin; Osimhiarherhuo Ohifemen; Abubabkar A Sani; Eric Tabi-Ajayi; Ibinaiye O Phillip; Suleiman Y Isah; Nasir A Tabari; Aliyu Mande; Atinuke M Agunloye; Godwin I Ogbole; Joshua O Akinyemi; Onoja M Akpa; Ruth Laryea; Sylvia Ezinne Melikam; Dorcas Adinku; Ezinne Uvere; Nina-Serena Burkett; Gregory F Adekunle; Salaam I Kehinde; Paschal C Azuh; Abdul H Dambatta; Naser A Ishaq; Donna Arnett; Hemant K Tiwari; Dan Lackland; Mayowa Owolabi Journal: Neuroepidemiology Date: 2015-08-19 Impact factor: 3.282
Authors: Mark Kaddumukasa; James Kayima; Jane Nakibuuka; Leviticus Mugenyi; Edward Ddumba; Carol Blixen; Elisabeth Welter; Elly Katabira; Martha Sajatovic Journal: Cogent Med Date: 2017-05-19
Authors: Isaac Mugwano; Mark Kaddumukasa; Levi Mugenyi; James Kayima; Edward Ddumba; Martha Sajatovic; Cathy Sila; Michael DeGeorgia; Elly Katabira Journal: BMC Res Notes Date: 2016-01-02