Literature DB >> 18595139

Inoperable esophageal cancer and outcome of palliative care.

Sima Besharat1, Ali Jabbari, Shahryar Semnani, Abbasali Keshtkar, Jeran Marjani.   

Abstract

AIM: To determine the outcome of esophageal cancer patients referred for palliative care, in Gorgan and Gonbad gastrointestinal clinics, northeast of Iran.
METHODS: This cross-sectional study was done on inoperable esophageal cancer cases referred to gastrointestinal clinics in Gorgan and Gonbad city (2005-2006). Demographic data were collected during the procedure and cases were followed up every one month. Improvement proportion was calculated with 95% confidence interval, to determine the rate of improvement. Survival analysis and Kaplan-Meier methods were used to estimate the duration of palliative care effectiveness.
RESULTS: We recruited 39 cases into the study. Squamous cell carcinoma was the most prevalent (92.3%). The middle third of the esophagus was involved predominantly (51.3%). Dilation was the most preferred method (89.7%) and stenting was done in 4 cases. Decreasing dysphagia score was not related to palliation method or pathology type of carcinoma. Age of the patients was significantly related to the improvement of dysphagia score. Mean survival time was 137.6 d and median was 103 d.
CONCLUSION: Results of this study showed a low survival rate after palliative care in esophageal cancer cases despite dysphagia scores' improvement after dilating or stenting.

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Year:  2008        PMID: 18595139      PMCID: PMC2719235          DOI: 10.3748/wjg.14.3725

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  15 in total

1.  [Stent insertion as palliation of cancer in the esophagus and cardia].

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Journal:  Tidsskr Nor Laegeforen       Date:  2006-06-08

2.  Outcome of palliative care regimens in patients with advanced oesophageal cancer detected during explorative surgery.

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5.  Undernutrition is predictive of early mortality after palliative self-expanding metal stent insertion in patients with inoperable or recurrent esophageal cancer.

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Journal:  Gastrointest Endosc       Date:  2006-07-26       Impact factor: 9.427

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9.  Palliative treatment of obstructing esophageal cancer with nitinol stents: value, safety, and long-term results.

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10.  [Treatment of dysphagia of malignant origin with the endoprosthesis of Strecker].

Authors:  J M Carreira; E Górriz; R Reyes; J M Argilés; J M Pulido; M D Pardo; M Maynar
Journal:  Med Clin (Barc)       Date:  1998-05-30       Impact factor: 1.725

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  17 in total

1.  New serum biomarkers for detection of esophageal carcinoma using Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Authors:  Renyong Guo; Chunqin Pan; Jianmin Shen; Chibo Liu
Journal:  J Cancer Res Clin Oncol       Date:  2010-05-21       Impact factor: 4.553

2.  Palliative interventions for patients with incurable locally advanced or metastatic thoracic esophageal carcinoma.

Authors:  Tomoyuki Kakuta; Shin-Ichi Kosugi; Hiroshi Ichikawa; Takaaki Hanyu; Takashi Ishikawa; Tatsuo Kanda; Toshifumi Wakai
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3.  Clinical Effect and Postoperative Pain of Laparo-Thoracoscopic Esophagectomy in Patients with Esophageal Cancer.

Authors:  Yue Yu; Yun Han
Journal:  Evid Based Complement Alternat Med       Date:  2022-06-26       Impact factor: 2.650

Review 4.  Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma.

Authors:  Jin Lv; Xiu-Feng Cao; Bin Zhu; Lv Ji; Lei Tao; Dong-Dong Wang
Journal:  World J Gastroenterol       Date:  2009-10-21       Impact factor: 5.742

5.  Serum clusterin as a tumor marker and prognostic factor for patients with esophageal cancer.

Authors:  Wei Guo; Xiao Ma; Christine Xue; Jianfeng Luo; Xiaoli Zhu; Jiaqing Xiang; Bo Lu; Hecheng Li
Journal:  Dis Markers       Date:  2014-12-10       Impact factor: 3.434

6.  Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and staging.

Authors:  Jing Xu; Yanhua Chen; Ruiping Zhang; Jiuming He; Yongmei Song; Jingbo Wang; Huiqing Wang; Luhua Wang; Qimin Zhan; Zeper Abliz
Journal:  Sci Rep       Date:  2016-10-11       Impact factor: 4.379

7.  Investigating Esophageal Stent-Placement Outcomes in Patients with Inoperable Non-Cervical Esophageal Cancer.

Authors:  Mojgan Forootan; Morteza Tabatabaeefar; Nariman Mosaffa; Hormat Rahimzadeh Ashkalak; Mohammad Darvishi
Journal:  J Cancer       Date:  2018-01-01       Impact factor: 4.207

8.  Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).

Authors:  Weilin Pu; Chenji Wang; Sidi Chen; Dunmei Zhao; Yinghui Zhou; Yanyun Ma; Ying Wang; Caihua Li; Zebin Huang; Li Jin; Shicheng Guo; Jiucun Wang; Minghua Wang
Journal:  Clin Epigenetics       Date:  2017-12-15       Impact factor: 6.551

9.  Baicalein induces apoptosis in esophageal squamous cell carcinoma cells through modulation of the PI3K/Akt pathway.

Authors:  Hong-Bo Zhang; Ping Lu; Qing-Yin Guo; Zhen-Hua Zhang; Xiang-Yu Meng
Journal:  Oncol Lett       Date:  2012-12-10       Impact factor: 2.967

10.  Combined brachytherapy and external beam radiation: an effective approach for palliation in esophageal cancer.

Authors:  Sarbani Ghosh Laskar; Shirley Lewis; Jai Prakash Agarwal; Shagun Mishra; Shaesta Mehta; Prachi Patil
Journal:  J Contemp Brachytherapy       Date:  2015-12-30
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