Literature DB >> 16565659

[Palliative endoscopic treatments for esophageal cancers].

Laetitia Dahan1, Pauline Ries, René Laugier, Jean-François Seitz.   

Abstract

Esophageal cancer five-year survival has slightly increased during past 20 years (from 5 to 9%), but remains low. At time of diagnosis, 60% of the patients are only relevant for palliative therapy. Recent advances in therapeutic endoscopy have allowed improving dysphagia and quality of life. Endoscopic techniques are chosen according to tumor characteristics. According to French societies guidelines (FFCD, "Standards-Options-Recommandations" from FNCLCC, SNFGE) endoscopic treatment is a "gold standard" for metastatic patients with poor performance status, as well as oesophago-tracheal fistula. Expandable metal stent are efficient for malignant stenosis with lower morbidity and mortality than plastic prosthesis. Endoscopic placement of a covered self-expanding metal stent is the treatment of choice of an esophago-respiratory fistula. Dilatation is often the first step before other endoscopic therapies or medical treatment such as radiochemotherapy. Single dose brachytherapy could provide better long-term relief of dysphagia and fewer complications than stent placement, but is less widespread. Other techniques like bipolar electrocoagulation have restricted indications especially for circonferential stenosis of cervical esophagus. However, the main problem remains the dysphagia relapse after treatment.

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Year:  2006        PMID: 16565659     DOI: 10.1016/s0399-8320(06)73162-1

Source DB:  PubMed          Journal:  Gastroenterol Clin Biol        ISSN: 0399-8320


  3 in total

Review 1.  MR thermometry for monitoring tumor ablation.

Authors:  Baudouin Denis de Senneville; Charles Mougenot; Bruno Quesson; Iulius Dragonu; Nicolas Grenier; Chrit T W Moonen
Journal:  Eur Radiol       Date:  2007-05-22       Impact factor: 5.315

2.  Inoperable esophageal cancer and outcome of palliative care.

Authors:  Sima Besharat; Ali Jabbari; Shahryar Semnani; Abbasali Keshtkar; Jeran Marjani
Journal:  World J Gastroenterol       Date:  2008-06-21       Impact factor: 5.742

3.  Airway and esophageal stenting in patients with advanced esophageal cancer and pulmonary involvement.

Authors:  Fabrice Paganin; Laurent Schouler; Laurent Cuissard; Jean Baptiste Noel; Jean-Philippe Becquart; Mathieu Besnard; Laurent Verdier; Denis Rousseau; Claude Arvin-Berod; Arnaud Bourdin
Journal:  PLoS One       Date:  2008-08-29       Impact factor: 3.240

  3 in total

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