Literature DB >> 18585889

Improved diagnosis and treatment of anastomotic leakage after colorectal surgery.

M den Dulk1, S L Noter, E R Hendriks, M A M Brouwers, C H van der Vlies, R J Oostenbroek, A G Menon, W H Steup, C J H van de Velde.   

Abstract

AIM: This study aimed at testing feasibility of a standardised postoperative surveillance protocol to reduce delay in the diagnosis of anastomotic leakage (AL) and, subsequently, mortality.
MATERIAL AND METHODS: Patient files of patients operated between 1996 and 1999 were reviewed and used as historical controls (n=1066). As a result, a protocol for standardised post-operative surveillance was designed using easily accessible, clinical parameters. Between August 2004 and August 2006, all operated patients with a colorectal anastomosis (n=223) were prospectively subjected to this standardised surveillance.
RESULTS: AL was diagnosed in 7.0% of patients in the historical control group and 9.4% of patients in the standardised surveillance group. AL mortality decreased from 39% to 24% with standardised surveillance (n.s.). The delay in AL diagnosis was significantly reduced during standardised surveillance (4 versus 1.5 days, p=0.01), which was confirmed in the multivariate analysis.
CONCLUSION: With non-standardised postoperative monitoring, AL was associated with a high mortality rate. Patients were subjected to several additional tests, which were not primarily useful to diagnose AL. Standardised postoperative surveillance for AL was introduced successfully and resulted in a shorter delay between the first signs and symptoms to the confirmation of AL.

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Year:  2008        PMID: 18585889     DOI: 10.1016/j.ejso.2008.04.009

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  38 in total

1.  Early detection of anastomotic leakage after elective low anterior resection.

Authors:  Elyamani Fouda; Ayman El Nakeeb; Alaa Magdy; Enas A Hammad; Gamal Othman; Mohamed Farid
Journal:  J Gastrointest Surg       Date:  2010-10-27       Impact factor: 3.452

Review 2.  Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage.

Authors:  Sami A Chadi; Abe Fingerhut; Mariana Berho; Steven R DeMeester; James W Fleshman; Neil H Hyman; David A Margolin; Joseph E Martz; Elisabeth C McLemore; Daniela Molena; Martin I Newman; Janice F Rafferty; Bashar Safar; Anthony J Senagore; Oded Zmora; Steven D Wexner
Journal:  J Gastrointest Surg       Date:  2016-09-16       Impact factor: 3.452

3.  Polymerase chain reaction for Enterococcus faecalis in drain fluid: the first screening test for symptomatic colorectal anastomotic leakage. The Appeal-study: analysis of parameters predictive for evident anastomotic leakage.

Authors:  Niels Komen; Juliette Slieker; Paul Willemsen; Guido Mannaerts; Piet Pattyn; Tom Karsten; Hans de Wilt; Erwin van der Harst; Willem van Leeuwen; Christine Decaestecker; Hans Jeekel; Johan F Lange
Journal:  Int J Colorectal Dis       Date:  2014-01       Impact factor: 2.571

4.  Protection of intestinal anastomosis with biological glues: an experimental randomized controlled trial.

Authors:  S Giuratrabocchetta; M Rinaldi; F Cuccia; M Lemma; D Piscitelli; P Polidoro; D F Altomare
Journal:  Tech Coloproctol       Date:  2011-01-25       Impact factor: 3.781

5.  Identification of anastomotic leakage after colorectal surgery using microdialysis of the peritoneal cavity.

Authors:  F Daams; Z Wu; H Cakir; T M Karsten; J F Lange
Journal:  Tech Coloproctol       Date:  2013-04-30       Impact factor: 3.781

6.  Colorectal anastomotic leakage: aspects of prevention, detection and treatment.

Authors:  Freek Daams; Misha Luyer; Johan F Lange
Journal:  World J Gastroenterol       Date:  2013-04-21       Impact factor: 5.742

Review 7.  Management of Colorectal Anastomotic Leak.

Authors:  Michael S Thomas; David A Margolin
Journal:  Clin Colon Rectal Surg       Date:  2016-06

Review 8.  Prediction and diagnosis of colorectal anastomotic leakage: A systematic review of literature.

Authors:  Freek Daams; Zhouqiao Wu; Max Jef Lahaye; Johannus Jeekel; Johan Frederik Lange
Journal:  World J Gastrointest Surg       Date:  2014-02-27

Review 9.  Improving the outcomes in oncological colorectal surgery.

Authors:  Jeroen L A van Vugt; Kostan W Reisinger; Joep P M Derikx; Djamila Boerma; Jan H M B Stoot
Journal:  World J Gastroenterol       Date:  2014-09-21       Impact factor: 5.742

10.  Cytokine response in peripheral blood indicates different pathophysiological mechanisms behind anastomotic leakage after low anterior resection: a pilot study.

Authors:  M B Ellebæk; G Baatrup; J Gjedsted; C Fristrup; N Qvist
Journal:  Tech Coloproctol       Date:  2014-08-23       Impact factor: 3.781

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