Literature DB >> 18584361

Fentanyl epidemic in Chicago, Illinois and surrounding Cook County.

Heather Schumann1, Tim Erickson, Trevonne M Thompson, John L Zautcke, J Scott Denton.   

Abstract

INTRODUCTION: Epidemics related to illicit fentanyl abuse have been reported and the potential exists for a national epidemic associated with high mortality. This report describes emergency department visits for opioid toxicity and a recent outbreak of illicit fentanyl fatalities in Chicago, Illinois and surrounding Cook County.
METHODS: Retrospective chart review of opioid-related overdoses seen in our emergency department and a retrospective review of data from the Cook County Medical Examiner's Office Fentanyl Fatality Database from April 2005 through December 2006.
RESULTS: Our emergency department treated 43 patients with a total of 55 emergency department visits during this time. Paramedic transport was utilized for 83.6% of the emergency department visits and naloxone was administered during 80.4% of transports. Naloxone was administered during 47.3% of emergency department visits with total doses ranging from 0.4 mg to 12 mg. Eighty percent of cases were treated and discharged from the emergency department. During this same time frame, the Medical Examiner's office identified 342 fentanyl-related fatalities. In 2006, illicit fentanyl fatalities represented 6.9% of all Medical Examiner cases for that year. Approximately 80% of deaths occurred in Chicago. A peak in fentanyl-related deaths occurred in the spring of 2006 and again in the fall of 2006 while the number of emergency department visits peaked during May of 2006.
CONCLUSION: Chicago and surrounding Cook County experienced an outbreak of 342 fentanyl-related deaths between April 2005 and December 2006. The experience demonstrated a clear need for an interdisciplinary approach to identifying, communicating, and managing an outbreak.

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Year:  2008        PMID: 18584361     DOI: 10.1080/15563650701877374

Source DB:  PubMed          Journal:  Clin Toxicol (Phila)        ISSN: 1556-3650            Impact factor:   4.467


  29 in total

1.  Carfentanil-Associated Mortality in Wayne County, Michigan, 2015-2017.

Authors:  Andrew King; Daniel Foley; Cynthia Arfken; Cynthia Aaron; Lokman Sung; Leigh Hlavaty
Journal:  Am J Public Health       Date:  2018-12-20       Impact factor: 9.308

2.  Heroin uncertainties: Exploring users' perceptions of fentanyl-adulterated and -substituted 'heroin'.

Authors:  Daniel Ciccarone; Jeff Ondocsin; Sarah G Mars
Journal:  Int J Drug Policy       Date:  2017-07-18

3.  Naloxone Dosing After Opioid Overdose in the Era of Illicitly Manufactured Fentanyl.

Authors:  Joseph Carpenter; Brian Patrick Murray; Sukhshant Atti; Tim P Moran; Arthur Yancey; Brent Morgan
Journal:  J Med Toxicol       Date:  2019-08-30

4.  Novel Synthetic Opioids and Overdose Deaths: Tip of the Iceberg?

Authors:  Michael H Baumann; Gavril W Pasternak
Journal:  Neuropsychopharmacology       Date:  2018-01       Impact factor: 7.853

5.  Postmortem Toxicology Findings of Acetyl Fentanyl, Fentanyl, and Morphine in Heroin Fatalities in Tampa, Florida.

Authors:  Julia Pearson; Justin Poklis; Alphonse Poklis; Carl Wolf; Mary Mainland; Laura Hair; Kelly Devers; Leszek Chrostowski; Elise Arbefeville; Michele Merves
Journal:  Acad Forensic Pathol       Date:  2015-12

6.  Safety of a Modified Community Trailer to Manage Patients with Presumed Fentanyl Overdose.

Authors:  Frank X Scheuermeyer; Eric Grafstein; Jane Buxton; Keith Ahamad; Mark Lysyshyn; Stan DeVlaming; Gerrit Prinsloo; Christopher Van Veen; Andrew Kestler; Reka Gustafson
Journal:  J Urban Health       Date:  2019-02       Impact factor: 3.671

7.  Sold as Heroin: Perceptions and Use of an Evolving Drug in Baltimore, MD.

Authors:  Sarah G Mars; Jeff Ondocsin; Daniel Ciccarone
Journal:  J Psychoactive Drugs       Date:  2017-12-06

8.  Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors.

Authors:  Hang Lin; Paul Higgins; Horace H Loh; Ping-Yee Law; Dezhi Liao
Journal:  Neuropsychopharmacology       Date:  2009-03-18       Impact factor: 7.853

Review 9.  An overview of the patterns of prescription opioid use, costs and related harms in Australia.

Authors:  Bianca Blanch; Sallie-Anne Pearson; Paul S Haber
Journal:  Br J Clin Pharmacol       Date:  2014-11       Impact factor: 4.335

10.  Comparison of two automated solid phase extractions for the detection of ten fentanyl analogs and metabolites in human urine using liquid chromatography tandem mass spectrometry.

Authors:  Rebecca L Shaner; Pearl Kaplan; Elizabeth I Hamelin; William A Bragg; Rudolph C Johnson
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2014-05-24       Impact factor: 3.205

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