Literature DB >> 28735775

Heroin uncertainties: Exploring users' perceptions of fentanyl-adulterated and -substituted 'heroin'.

Daniel Ciccarone1, Jeff Ondocsin2, Sarah G Mars2.   

Abstract

BACKGROUND: The US is experiencing an unprecedented opioid overdose epidemic fostered in recent years by regional contamination of the heroin supply with the fentanyl family of synthetic opioids. Since 2011 opioid-related overdose deaths in the East Coast state of Massachusetts have more than tripled, with 75% of the 1374 deaths with an available toxicology positive for fentanyl. Fentanyl is 30-50X more potent than heroin and its presence makes heroin use more unpredictable. A rapid ethnographic assessment was undertaken to understand the perceptions and experiences of people who inject drugs sold as 'heroin' and to observe the drugs and their use.
METHODS: A team of ethnographers conducted research in northeast Massachusetts and Nashua, New Hampshire in June 2016, performing (n=38) qualitative interviews with persons who use heroin.
RESULTS: (1) The composition and appearance of heroin changed in the last four years; (2) heroin is cheaper and more widely available than before; and (3) heroin 'types' have proliferated with several products being sold as 'heroin'. These consisted of two types of heroin (alone), fentanyl (alone), and heroin-fentanyl combinations. In the absence of available toxicological information on retail-level heroin, our research noted a hierarchy of fentanyl discernment methods, with embodied effects considered most reliable in determining fentanyl's presence, followed by taste, solution appearance and powder color. This paper presents a new 'heroin' typology based on users' reports.
CONCLUSION: Massachusetts' heroin has new appearances and is widely adulterated by fentanyl. Persons who use heroin are trying to discern the substances sold as heroin and their preferences for each form vary. The heroin typology presented is inexact but can be validated by correlating users' discernment with drug toxicological testing. If validated, this typology would be a valuable harm reduction tool. Further research on adaptations to heroin adulteration could reduce risks of using heroin and synthetic opioid combinations.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Fentanyl; Heroin; Mortality; Opioids; Overdose; Qualitative research

Mesh:

Substances:

Year:  2017        PMID: 28735775      PMCID: PMC5577861          DOI: 10.1016/j.drugpo.2017.06.004

Source DB:  PubMed          Journal:  Int J Drug Policy        ISSN: 0955-3959


  42 in total

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10.  Attitudes about prescribing take-home naloxone to injection drug users for the management of heroin overdose: a survey of street-recruited injectors in the San Francisco Bay Area.

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  81 in total

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2.  Adulterants and altruism: A qualitative investigation of "drug checkers" in North America.

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3.  Fentanyl in the US heroin supply: A rapidly changing risk environment.

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4.  Determining spatial access to opioid use disorder treatment and emergency medical services in New Hampshire.

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5.  Emerging threats in addiction: will novel psychoactive substances contribute to exacerbating the ongoing drug overdose epidemic?

Authors:  F Scott Hall; Klaus A Miczek
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6.  Community-Based Response to Fentanyl Overdose Outbreak, San Francisco, 2015.

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Journal:  J Urban Health       Date:  2019-02       Impact factor: 3.671

7.  Effects of heroin on rat prosocial behavior.

Authors:  Seven E Tomek; Gabriela M Stegmann; M Foster Olive
Journal:  Addict Biol       Date:  2018-05-04       Impact factor: 4.280

8.  Understanding the increase in opioid overdoses in New Hampshire: A rapid epidemiologic assessment.

Authors:  Andrea Meier; Sarah K Moore; Elizabeth C Saunders; Bethany McLeman; Stephen A Metcalf; Samantha Auty; Olivia Walsh; Lisa A Marsch
Journal:  Drug Alcohol Depend       Date:  2020-02-07       Impact factor: 4.492

9.  Perceptions about fentanyl-adulterated heroin and overdose risk reduction behaviors among persons seeking treatment for heroin use.

Authors:  Michael D Stein; Shannon R Kenney; Bradley J Anderson; Genie L Bailey
Journal:  J Subst Abuse Treat       Date:  2019-07-13

10.  Testing hair for fentanyl exposure: a method to inform harm reduction behavior among individuals who use heroin.

Authors:  Joseph J Palamar; Alberto Salomone; Rachele Bigiarini; Marco Vincenti; Patricia Acosta; Babak Tofighi
Journal:  Am J Drug Alcohol Abuse       Date:  2019-01-02       Impact factor: 3.829

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