Literature DB >> 18561666

Energy spectra, sources, and shielding considerations for neutrons generated by a flattening filter-free Clinac.

Stephen F Kry1, Rebecca M Howell, Uwe Titt, Mohammad Salehpour, Radhe Mohan, Oleg N Vassiliev.   

Abstract

Neutron production is an unwanted result of high-energy radiation therapy and results in secondary exposure of patients and radiation therapists to radiation. Recent studies have shown that delivering therapy using a standard medical accelerator with the flattening filter removed may reduce neutron fluence by nearly 70% over the course of prostate intensity-modulated radiation therapy (IMRT). In the current study, the 197Au Bonner sphere technique was used to compare the neutron spectrum produced when the filter is present and when it is absent. In addition, the following was calculated: (1) the neutron-shielding parameters of source strength and ambient dose equivalent (H0) and (2) using the Monte Carlo technique, the sources of neutron production in the accelerator head. It was found that the neutron spectrum was nearly constant, regardless of the presence of the flattening filter; however, the total fluence and ambient dose equivalent over the course of prostate IMRT were more than 70% lower when the filter was removed. Similarly, shielding parameters were lower when the filter was removed. Finally, the primary collimator and jaws accounted for the majority of neutron production, both with and without the flattening filter; however, with the flattening filter removed, the upper jaw accounted for much more neutron production relative to when the filter was present. Ultimately, removal of the flattening filter may offer several clinical advantages, including a reduction in the dose from neutrons to the patient and to radiation personnel.

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Mesh:

Year:  2008        PMID: 18561666     DOI: 10.1118/1.2905029

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  13 in total

1.  Neutron spectra and dose equivalents calculated in tissue for high-energy radiation therapy.

Authors:  Stephen F Kry; Rebecca M Howell; Mohammad Salehpour; David S Followill
Journal:  Med Phys       Date:  2009-04       Impact factor: 4.071

Review 2.  A review on photoneutrons characteristics in radiation therapy with high-energy photon beams.

Authors:  Alireza Naseri; Asghar Mesbahi
Journal:  Rep Pract Oncol Radiother       Date:  2010-09-22

3.  Secondary neutron spectra from modern Varian, Siemens, and Elekta linacs with multileaf collimators.

Authors:  Rebecca M Howell; Stephen F Kry; Eric Burgett; Nolan E Hertel; David S Followill
Journal:  Med Phys       Date:  2009-09       Impact factor: 4.071

4.  Secondary neutron spectrum from 250-MeV passively scattered proton therapy: measurement with an extended-range Bonner sphere system.

Authors:  Rebecca M Howell; E A Burgett
Journal:  Med Phys       Date:  2014-09       Impact factor: 4.071

5.  Fidelity of dose delivery at high dose rate of volumetric modulated arc therapy in a truebeam linac with flattening filter free beams.

Authors:  Georgios Kalantzis; Jianguo Qian; Bin Han; Gary Luxton
Journal:  J Med Phys       Date:  2012-10

6.  Unflattened photon beams from the standard flattening filter free accelerators for radiotherapy: Advantages, limitations and challenges.

Authors:  Sunil Dutt Sharma
Journal:  J Med Phys       Date:  2011-07

7.  Stereotactic body radiation therapy for liver tumours using flattening filter free beam: dosimetric and technical considerations.

Authors:  Pietro Mancosu; Simona Castiglioni; Giacomo Reggiori; Maddalena Catalano; Filippo Alongi; Chiara Pellegrini; Stefano Arcangeli; Angelo Tozzi; Francesca Lobefalo; Antonella Fogliata; Piera Navarria; Luca Cozzi; Marta Scorsetti
Journal:  Radiat Oncol       Date:  2012-02-01       Impact factor: 3.481

Review 8.  A Review of Radiotherapy-Induced Late Effects Research after Advanced Technology Treatments.

Authors:  Wayne D Newhauser; Amy Berrington de Gonzalez; Reinhard Schulte; Choonsik Lee
Journal:  Front Oncol       Date:  2016-02-10       Impact factor: 6.244

9.  Monitor units are not predictive of neutron dose for high-energy IMRT.

Authors:  Roger A Hälg; Jürgen Besserer; Markus Boschung; Sabine Mayer; Uwe Schneider
Journal:  Radiat Oncol       Date:  2012-08-10       Impact factor: 3.481

10.  Re-irradiating spinal column metastases using IMRT and VMAT with and without flattening filter - a treatment planning study.

Authors:  Barbara Dobler; Amine Khemissi; Tina Obermeier; Matthias G Hautmann; Zaira Katsilieri; Oliver Kölbl
Journal:  Radiat Oncol       Date:  2016-03-01       Impact factor: 3.481

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