Literature DB >> 18544344

Spliceosomal immunophilins.

Annia Mesa1, Jason A Somarelli, Rene J Herrera.   

Abstract

The spliceosome is a dynamic, macromolecular complex, which removes non-protein-coding introns from pre-mRNA to form mature mRNA in a process known as splicing. This ribonucleoprotein assembly is comprised of five uridine-rich small nuclear RNAs (snRNAs) as well as over 300 proteins. In humans, several of the known proteinaceous splicing factors are members of the immunophilin superfamily. Immunophilins are peptidyl-prolyl cis-trans isomerases that catalyze the conversion of proteins from cis to trans at Xaa-Pro bonds. Our review of the data indicates that some members of this protein family are activators of spliceosomal proteins by way of folding and transport.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18544344      PMCID： PMC2546689          DOI： 10.1016/j.febslet.2008.06.006

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  56 in total

1.  Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin.

Authors:  U Reidt; K Reuter; T Achsel; D Ingelfinger; R Lührmann; R Ficner
Journal:  J Biol Chem       Date:  2000-03-17       Impact factor: 5.157

2.  Composition and functional characterization of the yeast spliceosomal penta-snRNP.

Authors:  Scott W Stevens; Daniel E Ryan; Helen Y Ge; Roger E Moore; Mary K Young; Terry D Lee; John Abelson
Journal:  Mol Cell       Date:  2002-01       Impact factor: 17.970

3.  A novel class of dual-family immunophilins.

Authors:  Brian Adams; Alla Musiyenko; Rajinder Kumar; Sailen Barik
Journal:  J Biol Chem       Date:  2005-04-21       Impact factor: 5.157

Review 4.  The spliceosome: a ribozyme at heart?

Authors:  Saba Valadkhan
Journal:  Biol Chem       Date:  2007-07       Impact factor: 3.915

5.  Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly.

Authors:  S M Barabino; B J Blencowe; U Ryder; B S Sproat; A I Lamond
Journal:  Cell       Date:  1990-10-19       Impact factor: 41.582

6.  A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor.

Authors:  D S Horowitz; A R Krainer
Journal:  Genes Dev       Date:  1997-01-01       Impact factor: 11.361

7.  Matrin CYP, an SR-rich cyclophilin that associates with the nuclear matrix and splicing factors.

Authors:  M J Mortillaro; R Berezney
Journal:  J Biol Chem       Date:  1998-04-03       Impact factor: 5.157

8.  Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide.

Authors:  Ulrich Reidt; Markus C Wahl; Dirk Fasshauer; David S Horowitz; Reinhard Lührmann; Ralf Ficner
Journal:  J Mol Biol       Date:  2003-08-01       Impact factor: 5.469

9.  Identification and characterisation of Schizosaccharomyces pombe cyclophilin 3, a cyclosporin A insensitive orthologue of human USA-CyP.

Authors:  Trevor J Pemberton; Stuart L Rulten; John E Kay
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2003-03-25       Impact factor: 3.205

10.  Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.

Authors:  Yen-I G Chen; Roger E Moore; Helen Y Ge; Mary K Young; Terry D Lee; Scott W Stevens
Journal:  Nucleic Acids Res       Date:  2007-05-30       Impact factor: 16.971
View more
  10 in total

Review 1.  Prolyl isomerases in gene transcription.

Authors:  Steven D Hanes
Journal:  Biochim Biophys Acta       Date:  2014-10-31

2.  Differential immunoglobulin class-mediated responses to components of the U1 small nuclear ribonucleoprotein particle in systemic lupus erythematosus and mixed connective tissue disease.

Authors:  A Mesa; J A Somarelli; W Wu; L Martinez; M B Blom; E L Greidinger; R J Herrera
Journal:  Lupus       Date:  2013-11       Impact factor: 2.911

3.  The Arabidopsis cyclophilin CYP18-1 facilitates PRP18 dephosphorylation and the splicing of introns retained under heat stress.

Authors:  Seung Hee Jo; Hyun Ji Park; Areum Lee; Haemyeong Jung; Jeong Mee Park; Suk-Yoon Kwon; Hyun-Soon Kim; Hyo-Jun Lee; Youn-Sung Kim; Choonkyun Jung; Hye Sun Cho
Journal:  Plant Cell       Date:  2022-05-24       Impact factor: 12.085

4.  A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR.

Authors:  Xingsheng Wang; Shaojie Zhang; Jiahai Zhang; Xiaojuan Huang; Chao Xu; Weiwei Wang; Zhijun Liu; Jihui Wu; Yunyu Shi
Journal:  J Biol Chem       Date:  2009-12-09       Impact factor: 5.157

5.  The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein.

Authors:  Christian M Stegmann; Reinhard Lührmann; Markus C Wahl
Journal:  PLoS One       Date:  2010-04-02       Impact factor: 3.240

6.  OsCYP21-4, a novel Golgi-resident cyclophilin, increases oxidative stress tolerance in rice.

Authors:  Sang S Lee; Hyun J Park; Won Y Jung; Areum Lee; Dae H Yoon; Young N You; Hyun-Soon Kim; Beom-Gi Kim; Jun C Ahn; Hye S Cho
Journal:  Front Plant Sci       Date:  2015-10-01       Impact factor: 5.753

Review 7.  Cyclophilins as modulators of viral replication.

Authors:  Stephen D Frausto; Emily Lee; Hengli Tang
Journal:  Viruses       Date:  2013-07-11       Impact factor: 5.048

8.  The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module.

Authors:  David Dilworth; Santosh K Upadhyay; Pierre Bonnafous; Amiirah Bibi Edoo; Sarah Bourbigot; Francy Pesek-Jardim; Geoff Gudavicius; Jason J Serpa; Evgeniy V Petrotchenko; Christoph H Borchers; Christopher J Nelson; Cameron D Mackereth
Journal:  Nucleic Acids Res       Date:  2017-11-16       Impact factor: 16.971

9.  In silico analysis of the cyclophilin repertoire of apicomplexan parasites.

Authors:  Jürgen Krücken; Gisela Greif; Georg von Samson-Himmelstjerna
Journal:  Parasit Vectors       Date:  2009-06-25       Impact factor: 3.876

10.  Comprehensive Identification of RNA-Binding Domains in Human Cells.

Authors:  Alfredo Castello; Bernd Fischer; Christian K Frese; Rastislav Horos; Anne-Marie Alleaume; Sophia Foehr; Tomaz Curk; Jeroen Krijgsveld; Matthias W Hentze
Journal:  Mol Cell       Date:  2016-07-21       Impact factor: 17.970
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.