Literature DB >> 18542096

Contemporary management of adult intramedullary spinal tumors-pathology and neurological outcomes related to surgical resection.

G Manzano1, B A Green, S Vanni, A D Levi.   

Abstract

STUDY
DESIGN: Retrospective chart review and review of the recent literature.
OBJECTIVES: To present our experience, over an 8-year period, with aggressive microsurgical resection of intramedullary spinal tumors in adults focusing on histology, microsurgical techniques, short-term neurological outcomes, complication avoidance and dorsal column dysfunction (DCD).
SETTING: University of Miami/Jackson Memorial Medical Center Miami, FL, USA.
METHODS: We conducted a retrospective review of a series of adult patients with intramedullary spinal tumors treated with microsurgical excision at the University of Miami/Jackson Memorial Medical Center between January 1997 and September 2005.
RESULTS: Histologic analysis revealed a predominance of ependymomas (50%) with astrocytomas only comprising 12.5% of the tumors. We found no significant difference in pre- and postoperative McCormick grades. Although patients did not manifest significant motor weakness postoperatively as a result of surgery, 43.6% of patients exhibited the signs and symptoms of DCD, resulting in significant postoperative morbidity.
CONCLUSION: We present a contemporary adult series of intramedullary spinal tumors. The most significant postoperative morbidity experienced by patients was DCD. The neurosurgeon should recognize the impact of these symptoms, prepare the patient and his/her family for the possibility of DCD, and minimize dorsal column manipulation in an attempt to decrease its prevalence.

Entities:  

Mesh:

Year:  2008        PMID: 18542096     DOI: 10.1038/sc.2008.51

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  19 in total

Review 1.  Cavernous malformations of central nervous system in pediatric patients: our single-centered experience in 50 patients and review of literature.

Authors:  Dattaraj Paramanand Sawarkar; Suveen Janmatti; Rajinder Kumar; Pankaj Kumar Singh; Hitesh Kumar Gurjar; Shashank Sharad Kale; Bhawani Shanker Sharma; Ashok Kumar Mahapatra
Journal:  Childs Nerv Syst       Date:  2017-06-20       Impact factor: 1.475

2.  Diagnosis and microsurgical treatment of spinal hemangioblastoma.

Authors:  Xuezhen Li; Jianzhen Wang; Jianxing Niu; Jiakang Hong; Yaohui Feng
Journal:  Neurol Sci       Date:  2016-02-23       Impact factor: 3.307

3.  Natural history of intramedullary spinal cord ependymoma in patients preferring nonoperative treatment.

Authors:  Bedjan Behmanesh; Florian Gessler; Stephan Dützmann; Daniel Dubinski; Lioba Imoehl; Volker Seifert; Matthias Setzer; Gerhard Marquardt
Journal:  J Neurooncol       Date:  2017-06-30       Impact factor: 4.130

Review 4.  Current Management and Treatment Modalities for Intramedullary Spinal Cord Tumors.

Authors:  Rupa G Juthani; Mark H Bilsky; Michael A Vogelbaum
Journal:  Curr Treat Options Oncol       Date:  2015-08

5.  Clinical analysis of 21 cases of spinal cord ependymoma : positive clinical results of gross total resection.

Authors:  Tuncay Kaner; Mehdi Sasani; Tunc Oktenoglu; Bilgehan Solmaz; Ali Cetin Sarloglu; Ali Fahir Ozer
Journal:  J Korean Neurosurg Soc       Date:  2010-02-28

Review 6.  Prognosis by tumor location in adults with intracranial ependymomas.

Authors:  Eli T Sayegh; Derick Aranda; Joseph M Kim; Taemin Oh; Andrew T Parsa; Michael C Oh
Journal:  J Clin Neurosci       Date:  2014-07-15       Impact factor: 1.961

7.  Multisegmental versus monosegmental intramedullary spinal cord ependymomas: perioperative neurological functions and surgical outcomes.

Authors:  Chenlong Yang; Jianjun Sun; Jingcheng Xie; Changcheng Ma; Bin Liu; Tao Wang; Xiaodong Chen; Jian Wu; Haibo Wu; Mei Zheng; Qing Chang; Jun Yang
Journal:  Neurosurg Rev       Date:  2021-05-14       Impact factor: 3.042

8.  Surgical management of intradural spinal cord tumors in children and young adults: A single-center experience with 50 patients.

Authors:  Neriman Özkan; Ramazan Jabbarli; Karsten Henning Wrede; Zeynep Sariaslan; Klaus Peter Stein; Philipp Dammann; Adrian Ringelstein; Ulrich Sure; Erol Ibrahim Sandalcioglu
Journal:  Surg Neurol Int       Date:  2015-12-08

9.  Infected lumbar dermoid cyst mimicking intramedullary spinal cord tumor: Observations and outcomes.

Authors:  Sudhakar Vadivelu; Sohum K Desai; Anna Illner; Thomas G Luerssen; Andrew Jea
Journal:  J Pediatr Neurosci       Date:  2014-01

10.  Management and outcome in adult intramedullary spinal cord tumours: a 20-year single institution experience.

Authors:  Azize Boström; Nina-Christine Kanther; Alexander Grote; Jan Boström
Journal:  BMC Res Notes       Date:  2014-12-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.