Literature DB >> 20224707

Clinical analysis of 21 cases of spinal cord ependymoma : positive clinical results of gross total resection.

Tuncay Kaner1, Mehdi Sasani, Tunc Oktenoglu, Bilgehan Solmaz, Ali Cetin Sarloglu, Ali Fahir Ozer.   

Abstract

OBJECTIVE: To evaluate the clinical results of gross total resection in the surgical approach to spinal ependymoma.
METHODS: Between June 1995 and May 2009, 13 males and 8 females (mean age 34) diagnosed with intramedullary or extramedullary spinal ependymoma were surgically treated at our centre. The neurological and functional state of each patient were evaluated according to the modified McCormick scale.
RESULTS: The average follow-up duration was 54 months (ranging from 12 to 168 months). The locations of the lesions were: thoracic region (4, 19%), lumbar region (7, 34%), cervical region (4, 19%), cervicothoracic region (3, 14%) and conus medullaris (3, 14%). Four patients (19%) had deterioration of neurological function in the early postoperative period. The neurological function of three patients was completely recovered at the 6th postoperative month, while that of another patient was recovered at the 14th month. In the last assessment of neurological function, 20 patients (95%) were assessed as McCormick grade 1. No perioperative complications developed in any of our patients. In one patient's 24-month assessment, tumour recurrence was observed. Re-operation was not performed and the patient was taken under observation.
CONCLUSION: Two determinants of good clinical results after spinal ependymoma surgery are a gross total resection of the tumour and a good neurological condition before the operation. Although neurological deficits in the early postoperative period can develop as a result of gross total tumour resection, significant improvement is observed six months after the operation.

Entities:  

Keywords:  Ependymoma; Functional outcome; Intramedullary ependymoma; Intramedullary tumour

Year:  2010        PMID: 20224707      PMCID: PMC2836443          DOI: 10.3340/jkns.2010.47.2.102

Source DB:  PubMed          Journal:  J Korean Neurosurg Soc        ISSN: 1225-8245


  24 in total

1.  Spinal cord ependymoma: radical surgical resection and outcome.

Authors:  Fadi Hanbali; Daryl R Fourney; Eric Marmor; Dima Suki; Laurence D Rhines; Jeffrey S Weinberg; Ian E McCutcheon; Ian Suk; Ziya L Gokaslan
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Review 2.  Intramedullary tumors in adults.

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Authors:  T H Schwartz; P C McCormick
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4.  Long-term follow-up of intramedullary spinal cord tumors: a series of 202 cases.

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6.  Functional outcome after surgical treatment of intramedullary spinal cord tumors: experience with 78 patients.

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7.  MRI features of intramedullary spinal cord ependymomas.

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8.  Adult intramedullary spinal cord ependymomas: the result of surgery in 38 patients.

Authors:  F J Epstein; J P Farmer; D Freed
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9.  Surgical treatment of primary spinal tumors in the conus medullaris.

Authors:  In-Ho Han; Sung-Uk Kuh; Dong-Kyu Chin; Keun-Su Kim; Byung-Ho Jin; Yong-Eun Cho
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10.  Surgical results of 100 intramedullary tumors in relation to accompanying syringomyelia.

Authors:  M Samii; J Klekamp
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  15 in total

1.  Histologic grade and extent of resection are associated with survival in pediatric spinal cord ependymomas.

Authors:  Michael Safaee; Michael C Oh; Joseph M Kim; Derick Aranda; Phiroz E Tarapore; Tene A Cage; Nalin Gupta; Andrew T Parsa
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3.  Intradural extramedullary spinal ependymoma: a case report of malignant transformation occurring.

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4.  Adjuvant radiotherapy delays recurrence following subtotal resection of spinal cord ependymomas.

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7.  Spinal ependymomas: benefits of extent of resection for different histological grades.

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Review 8.  Spinal cord ependymomas and the appearance of other de novo tumors: a systematic review.

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10.  Complete Versus Incomplete Surgical Resection in Intramedullary Ependymomas: A Systematic Review and Meta-analysis.

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