Literature DB >> 26908123

Diagnosis and microsurgical treatment of spinal hemangioblastoma.

Xuezhen Li1, Jianzhen Wang2, Jianxing Niu3, Jiakang Hong2, Yaohui Feng2.   

Abstract

Spinal cord hemangioblastomas are rare benign tumors, with difficult surgical management and poor prognosis due to high vascularization. We aim to evaluate the diagnostic methods and microsurgical treatment of spinal cord hemangioblastoma. This retrospective study assessed 25 patients treated for spinal hemangioblastoma using microsurgery at Beijing Tiantan Hospital and Department of Neurosurgery, The General Hospital of Chinese People's Armed Police Forces, between October 2008 and October 2013. Clinical, imaging, and treatment data were collected. Meanwhile, efficacy was assessed with the McCormick grading system for spinal cord function. The symptoms lasted 17.0 ± 15.1 months. Sixteen (64 %) patients were suffering from von Hippel-Lindau disease; magnetic resonance imaging revealed the lesions in all patients. Intraoperative fluorescence angiography was helpful in identifying the feeding arteries and draining veins. Total tumor removal was achieved in all subjects. Patients were followed up for 21.3 ± 8.5 months. One week after surgery, neurological symptoms were improved in 22 patients, remained stable in 2 patients, and were aggravated in 1. The latter patient began to recover 7-10 days after surgery and was completely recovered within a month. At the last follow-up, all patients were alive, and all showed a McCormick grade ≤II. Microsurgery seems effective in the treatment of spinal cord hemangioblastoma. Intraoperative fluorescence angiography is helpful in defining the resection scope, to reduce intraoperative bleeding and prevent spinal swelling, which results in improved success rate.

Entities:  

Keywords:  Fluorescence angiography; Hemangioblastoma; Microsurgery; Spinal cord

Mesh:

Year:  2016        PMID: 26908123     DOI: 10.1007/s10072-016-2508-y

Source DB:  PubMed          Journal:  Neurol Sci        ISSN: 1590-1874            Impact factor:   3.307


  34 in total

1.  Hemangioblastomas of the central nervous system. A 10-year study with special reference to von Hippel-Lindau syndrome.

Authors:  H P Neumann; H R Eggert; K Weigel; H Friedburg; O D Wiestler; P Schollmeyer
Journal:  J Neurosurg       Date:  1989-01       Impact factor: 5.115

2.  Clinical features and natural history of von Hippel-Lindau disease.

Authors:  E R Maher; J R Yates; R Harries; C Benjamin; R Harris; A T Moore; M A Ferguson-Smith
Journal:  Q J Med       Date:  1990-11

3.  Prospective evaluation of surgical microscope-integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery.

Authors:  Andreas Raabe; Peter Nakaji; Jürgen Beck; Louis J Kim; Frank P K Hsu; Jonathan D Kamerman; Volker Seifert; Robert F Spetzler
Journal:  J Neurosurg       Date:  2005-12       Impact factor: 5.115

4.  Differentiation of localization of spinal hemangioblastomas based on imaging and pathological findings.

Authors:  Shiro Imagama; Zenya Ito; Norimitsu Wakao; Yoshihito Sakai; Fumihiko Kato; Yasutsugu Yukawa; Koji Sato; Kei Ando; Kenichi Hirano; Ryoji Tauchi; Akio Muramoto; Yoshio Hashizume; Yukihiro Matsuyama; Naoki Ishiguro
Journal:  Eur Spine J       Date:  2011-04-29       Impact factor: 3.134

5.  Spinal cord hemangioblastoma : diagnosis and clinical outcome after surgical treatment.

Authors:  Joon Ho Na; Hyeong Soo Kim; Whan Eoh; Jong Hyun Kim; Jong Soo Kim; Eun-Sang Kim
Journal:  J Korean Neurosurg Soc       Date:  2007-12-20

6.  Intracarotid fluorescein angiography: a new method for examination of the epicerebral circulation in man.

Authors:  W Feindel; Y L Yamamoto; C P Hodge
Journal:  Can Med Assoc J       Date:  1967-01-07       Impact factor: 8.262

7.  Near-infrared indocyanine green video angiography: a new method for intraoperative assessment of vascular flow.

Authors:  Andreas Raabe; Jürgen Beck; Rüdiger Gerlach; Michael Zimmermann; Volker Seifert
Journal:  Neurosurgery       Date:  2003-01       Impact factor: 4.654

Review 8.  von Hippel-Lindau disease.

Authors:  Russell R Lonser; Gladys M Glenn; McClellan Walther; Emily Y Chew; Steven K Libutti; W Marston Linehan; Edward H Oldfield
Journal:  Lancet       Date:  2003-06-14       Impact factor: 79.321

9.  Spinal cord hemangioblastomas in von Hippel-Lindau disease.

Authors:  H Kanno; I Yamamoto; R Nishikawa; M Matsutani; T Wakabayashi; J Yoshida; N Shitara; I Yamasaki; T Shuin
Journal:  Spinal Cord       Date:  2008-11-25       Impact factor: 2.772

10.  Surgical results of 100 intramedullary tumors in relation to accompanying syringomyelia.

Authors:  M Samii; J Klekamp
Journal:  Neurosurgery       Date:  1994-11       Impact factor: 4.654

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  3 in total

1.  Hydrocephalus: a rare initial manifestation of sporadic intramedullary hemangioblastoma : Intramedullary hemangioblastoma presenting as hydrocephalus.

Authors:  Barbara Albuquerque Morais; Daniel Dante Cardeal; Renan Ribeiro E Ribeiro; Fernando Pereira Frassetto; Fernanda Goncalves Andrade; Hamilton Matushita; Manoel Jacobsen Teixeira
Journal:  Childs Nerv Syst       Date:  2017-04-25       Impact factor: 1.475

Review 2.  Post-traumatic carotid-cavernous fistula in a pediatric patient: a case-based literature review.

Authors:  Barbara Albuquerque Morais; Vitor Nagai Yamaki; Jose Guilherme Mendes Pereira Caldas; Wellingson Silva Paiva; Hamilton Matushita; Manoel Jacobsen Teixeira
Journal:  Childs Nerv Syst       Date:  2017-11-23       Impact factor: 1.475

3.  Microsurgical Resection of Spinal Cord Hemangioblastoma: 2-Dimensional Operative Video.

Authors:  Mirza Pojskic; Kenan I Arnautovic
Journal:  Oper Neurosurg (Hagerstown)       Date:  2018-12-01       Impact factor: 2.703

  3 in total

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