PURPOSE: To explore the sensitivity and specificity of ultrasonographic (US) elastography using carotid arterial pulsation as the compression source for differential diagnosis of thyroid nodules. MATERIALS AND METHODS: This HIPAA-compliant study was approved by the ethics committee of the institution, and all patients provided written informed consent. Fifty-eight patients (13 men and 45 women [mean age, 51 years; range, 20-76 years]) were enrolled. A short US examination and elastography with pulsation of the carotid artery used as the thyroid compression source were performed before fine-needle aspiration. Baseband US data were downloaded for off-line analysis. Elastographic maps and the thyroid stiffness index were calculated. The Kruskal-Wallis nonparametric rank sum test was used to assess equality of population medians among the different types of thyroid nodules; the R software environment was used for statistical computing and graphics (http://www.r-project.org/). RESULTS: Thyroid stiffness index calculated with elastography using carotid arterial pulsation as the compression source was effective in helping distinguish between papillary carcinomas (n = 10) and other lesions (n = 43) because papillary carcinomas were stiffer than other lesions (P < .0039). CONCLUSION: It is possible to distinguish between papillary carcinomas and other lesions with the thyroid stiffness index calculated from US elastography using carotid arterial pulsation.
PURPOSE: To explore the sensitivity and specificity of ultrasonographic (US) elastography using carotid arterial pulsation as the compression source for differential diagnosis of thyroid nodules. MATERIALS AND METHODS: This HIPAA-compliant study was approved by the ethics committee of the institution, and all patients provided written informed consent. Fifty-eight patients (13 men and 45 women [mean age, 51 years; range, 20-76 years]) were enrolled. A short US examination and elastography with pulsation of the carotid artery used as the thyroid compression source were performed before fine-needle aspiration. Baseband US data were downloaded for off-line analysis. Elastographic maps and the thyroid stiffness index were calculated. The Kruskal-Wallis nonparametric rank sum test was used to assess equality of population medians among the different types of thyroid nodules; the R software environment was used for statistical computing and graphics (http://www.r-project.org/). RESULTS: Thyroid stiffness index calculated with elastography using carotid arterial pulsation as the compression source was effective in helping distinguish between papillary carcinomas (n = 10) and other lesions (n = 43) because papillary carcinomas were stiffer than other lesions (P < .0039). CONCLUSION: It is possible to distinguish between papillary carcinomas and other lesions with the thyroid stiffness index calculated from US elastography using carotid arterial pulsation.
Authors: Kunwar S S Bhatia; Cina S L Tong; Carmen C M Cho; Edmund H Y Yuen; Yolanda Y P Lee; Anil T Ahuja Journal: Eur Radiol Date: 2012-05-30 Impact factor: 5.315
Authors: Mohammad Mehrmohammadi; Pengfei Song; Duane D Meixner; Robert T Fazzio; Shigao Chen; James F Greenleaf; Mostafa Fatemi; Azra Alizad Journal: IEEE Trans Med Imaging Date: 2014-08-08 Impact factor: 10.048
Authors: S Merino; J Arrazola; A Cárdenas; M Mendoza; P De Miguel; C Fernández; T Ganado Journal: AJNR Am J Neuroradiol Date: 2011-11-03 Impact factor: 3.825
Authors: Christoph F Dietrich; Richard G Barr; André Farrokh; Manjiri Dighe; Michael Hocke; Christian Jenssen; Yi Dong; Adrian Saftoiu; Roald Flesland Havre Journal: Ultrasound Int Open Date: 2017-12-07