Literature DB >> 18521193

Green tea catechins suppress the DNA synthesis marker MCM7 in the TRAMP model of prostate cancer.

Susan McCarthy1, Andrea Caporali, Steve Enkemann, Maurizio Scaltriti, Steve Eschrich, Pierpaola Davalli, Arnaldo Corti, Alice Lee, Jimmy Sung, Timothy J Yeatman, Saverio Bettuzzi.   

Abstract

Green tea catechins (GTCs) exert chemopreventive effects in many cancer models. Several studies implicate the DNA synthesis marker minichromosome maintenance protein 7 (MCM7) in prostate cancer progression, growth and invasion; representing a novel therapeutic target. In this study, we investigated the effect of GTCs on MCM7 expression in the transgenic adenocarcinoma mouse prostate model (TRAMP). DNA microarray, immunohistochemistry and western blot analysis showed that GTCs significantly suppressed MCM7 in the TRAMP mice treated with GTCs. Our study indicates that the cellular DNA replication factor MCM7 is involved in prostate cancer (CaP) and MCM7 gene expression was reduced by GTCs. Together, these results suggest a possible role of GTCs in CaP chemoprevention in which MCM7 plays a critical role.

Entities:  

Keywords:  chemoprevention; green tea catechins; minichromosome maintenance protein 7; prostate cancer; transgenic adenocarcinoma mouse prostate model

Mesh：

Substances：

Year:  2007        PMID： 18521193      PMCID： PMC2408886          DOI： 10.1016/j.molonc.2007.05.007

Source DB:  PubMed          Journal:  Mol Oncol        ISSN： 1574-7891            Impact factor:   6.603


  38 in total

1.  The potential for prostate cancer chemoprevention.

Authors:  Otis W Brawley
Journal:  Rev Urol       Date:  2002

2.  Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols.

Authors:  S Gupta; K Hastak; N Ahmad; J S Lewin; H Mukhtar
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-14       Impact factor: 11.205

3.  Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F.

Authors:  K Ohtani; R Iwanaga; M Nakamura; M Ikeda; N Yabuta; H Tsuruga; H Nojima
Journal:  Oncogene       Date:  1999-04-08       Impact factor: 9.867

4.  Prognostic significance of metastasis-associated protein S100A4 (Mts1) in prostate cancer progression and chemoprevention regimens in an autochthonous mouse model.

Authors:  Mohammad Saleem; Vaqar Mustafa Adhami; Nihal Ahmad; Sanjay Gupta; Hasan Mukhtar
Journal:  Clin Cancer Res       Date:  2005-01-01       Impact factor: 12.531

5.  Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays.

Authors:  Kevin K Dobbin; David G Beer; Matthew Meyerson; Timothy J Yeatman; William L Gerald; James W Jacobson; Barbara Conley; Kenneth H Buetow; Mervi Heiskanen; Richard M Simon; John D Minna; Luc Girard; David E Misek; Jeremy M G Taylor; Samir Hanash; Katsuhiko Naoki; D Neil Hayes; Christine Ladd-Acosta; Steven A Enkemann; Agnes Viale; Thomas J Giordano
Journal:  Clin Cancer Res       Date:  2005-01-15       Impact factor: 12.531

Review 6.  Green tea polyphenols in the prevention of colon cancer.

Authors:  Nagi Kumar; David Shibata; James Helm; Domenico Coppola; Mokenge Malafa
Journal:  Front Biosci       Date:  2007-01-01

7.  Oral consumption of green tea polyphenols inhibits insulin-like growth factor-I-induced signaling in an autochthonous mouse model of prostate cancer.

Authors:  Vaqar Mustafa Adhami; Imtiaz Ahmad Siddiqui; Nihal Ahmad; Sanjay Gupta; Hasan Mukhtar
Journal:  Cancer Res       Date:  2004-12-01       Impact factor: 12.701

8.  DNA replication regulation protein Mcm7 as a marker of proliferation in prostate cancer.

Authors:  V Padmanabhan; P Callas; G Philips; T D Trainer; B G Beatty
Journal:  J Clin Pathol       Date:  2004-10       Impact factor: 3.411

Review 9.  Tea beverage in chemoprevention of prostate cancer: a mini-review.

Authors:  Mohammad Saleem; Vaqar Mustafa Adhami; Imtiaz Ahmad Siddiqui; Hasan Mukhtar
Journal:  Nutr Cancer       Date:  2003       Impact factor: 2.900

10.  Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer.

Authors:  Jun Yang; Nithya Ramnath; Kirsten B Moysich; Harold L Asch; Helen Swede; Sadir J Alrawi; Joel Huberman; Joseph Geradts; John S J Brooks; Dongfeng Tan
Journal:  BMC Cancer       Date:  2006-08-01       Impact factor: 4.430
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  11 in total

1.  Safety and chemopreventive effect of Polyphenon E in preventing early and metastatic progression of prostate cancer in TRAMP mice.

Authors:  Seung Joon Kim; Ernest Amankwah; Shahnjayla Connors; Hyun Y Park; Maria Rincon; Heather Cornnell; Ganna Chornokur; Arig Ibrahim Hashim; Junsung Choi; Ya-Yu Tsai; Robert W Engelman; Nagi Kumar; Jong Y Park
Journal:  Cancer Prev Res (Phila)       Date:  2014-02-05

2.  Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

Authors:  Laura Poliseno; Leonardo Salmena; Luisa Riccardi; Alessandro Fornari; Min Sup Song; Robin M Hobbs; Paolo Sportoletti; Shorheh Varmeh; Ainara Egia; Giuseppe Fedele; Lucia Rameh; Massimo Loda; Pier Paolo Pandolfi
Journal:  Sci Signal       Date:  2010-04-13       Impact factor: 8.192

Review 3.  Chemopreventive effects of tea in prostate cancer: green tea versus black tea.

Authors:  Susanne M Henning; Piwen Wang; David Heber
Journal:  Mol Nutr Food Res       Date:  2011-05-02       Impact factor: 5.914

Review 4.  Review: green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies.

Authors:  Naghma Khan; Vaqar Mustafa Adhami; Hasan Mukhtar
Journal:  Nutr Cancer       Date:  2009       Impact factor: 2.900

Review 5.  New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer.

Authors:  Shahnjayla K Connors; Ganna Chornokur; Nagi B Kumar
Journal:  Nutr Cancer       Date:  2011-11-18       Impact factor: 2.900

Review 6.  Green Tea Epigallocatechin-3-Gallate Regulates Autophagy in Male and Female Reproductive Cancer.

Authors:  Sze Wan Hung; Yiran Li; Xiaoyan Chen; Kai On Chu; Yiwei Zhao; Yingyu Liu; Xi Guo; Gene Chi-Wai Man; Chi Chiu Wang
Journal:  Front Pharmacol       Date:  2022-07-04       Impact factor: 5.988

Review 7.  Green tea polyphenols for prostate cancer chemoprevention: a translational perspective.

Authors:  J J Johnson; H H Bailey; H Mukhtar
Journal:  Phytomedicine       Date:  2010-01       Impact factor: 5.340

8.  Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate.

Authors:  Shannon R Morey Kinney; Wa Zhang; Marien Pascual; John M Greally; Bryan M Gillard; Ellen Karasik; Barbara A Foster; Adam R Karpf
Journal:  Cancer Prev Res (Phila)       Date:  2009-11-24

9.  Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease.

Authors:  Vaqar Mustafa Adhami; Imtiaz Ahmad Siddiqui; Sami Sarfaraz; Sabih Islam Khwaja; Bilal Bin Hafeez; Nihal Ahmad; Hasan Mukhtar
Journal:  Clin Cancer Res       Date:  2009-03-10       Impact factor: 12.531

Review 10.  Anticancer activity of green tea polyphenols in prostate gland.

Authors:  Pierpaola Davalli; Federica Rizzi; Andrea Caporali; Davide Pellacani; Serena Davoli; Saverio Bettuzzi; Maurizio Brausi; Domenico D'Arca
Journal:  Oxid Med Cell Longev       Date:  2012-05-15       Impact factor: 6.543
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