Literature DB >> 18519997

The preferences of adult outpatients in medical or dental care settings for giving saliva, urine or blood for clinical testing.

Sreenivas Koka1, Timothy J Beebe, Stephen P Merry, Ramona S DeJesus, Lorenzo D Berlanga, Amy L Weaver, Victor M Montori, David T Wong.   

Abstract

BACKGROUND: The design of new diagnostic tests would benefit from knowing patients' preferences for the collection of bodily fluids. These preferences, however, are unknown. The authors assessed patients' preferences for the collection of saliva, urine and blood as diagnostic fluids.
METHODS: The authors handed out surveys adult outpatients who sought treatment at two medical care sites and one dental care site at a medical center regarding the comfort, convenience and ease of collection of saliva, urine and blood for diagnostic testing.
RESULTS: A total of 413 surveys were completed. Subjects regarded the donation of saliva as more comfortable and convenient than that of blood or urine at the doctor's (physician's or dentist's) office, and they reported that saliva and urine are easiest to collect at home compared with blood. Male subjects and subjects who had ever donated saliva were more likely to perceive saliva donation in the doctor's office favorably. Subjects at all care sites regarded the donation of saliva as more comfortable and convenient than that of blood or urine; however, subjects at the dental care site perceived saliva donation more favorably than did subjects at the medical care sites. In addition, respondents said they were more willing to participate in research and medical testing if it required saliva donation rather than urine or blood collection.
CONCLUSIONS: In terms of convenience and comfort, saliva compared well with blood and urine as a diagnostic fluid for clinical and research testing. Patients who sought care at both medical and dental sites shared these perceptions. CLINICAL IMPLICATIONS: Given strong patient preferences, saliva may be the fluid of choice for the development and implementation of patient-centered diagnostic tests in research and practice.

Entities:  

Mesh:

Year:  2008        PMID: 18519997      PMCID: PMC2694856          DOI: 10.14219/jada.archive.2008.0255

Source DB:  PubMed          Journal:  J Am Dent Assoc        ISSN: 0002-8177            Impact factor:   3.634


  11 in total

Review 1.  A revolution in biomedical assessment: the development of salivary diagnostics.

Authors:  L A Tabak
Journal:  J Dent Educ       Date:  2001-12       Impact factor: 2.264

2.  The use of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry to detect putative breast cancer markers in saliva: a feasibility study.

Authors:  Charles F Streckfus; Lenora R Bigler; Michael Zwick
Journal:  J Oral Pathol Med       Date:  2006-05       Impact factor: 4.253

3.  The expression of the c-erbB-2 receptor protein in glandular salivary secretions.

Authors:  Charles F Streckfus; Lenora Bigler; Tracy Dellinger; Melinda Kuhn; Normand Chouinard; Xaoli Dai
Journal:  J Oral Pathol Med       Date:  2004-11       Impact factor: 4.253

4.  Towards a simple, saliva-based test for the detection of oral cancer 'oral fluid (saliva), which is the mirror of the body, is a perfect medium to be explored for health and disease surveillance'.

Authors:  David T Wong
Journal:  Expert Rev Mol Diagn       Date:  2006-05       Impact factor: 5.225

Review 5.  Implications for diagnostics in the biochemistry and physiology of saliva.

Authors:  Arie V Nieuw Amerongen; Antoon J M Ligtenberg; Enno C I Veerman
Journal:  Ann N Y Acad Sci       Date:  2007-02-15       Impact factor: 5.691

Review 6.  Systemic assessments utilizing saliva: part 1 general considerations and current assessments.

Authors:  Michael D Forde; Sreenivas Koka; Steven E Eckert; Alan B Carr; David T Wong
Journal:  Int J Prosthodont       Date:  2006 Jan-Feb       Impact factor: 1.681

7.  Why don't men seek help? Family physicians' perspectives on help-seeking behavior in men.

Authors:  F Tudiver; Y Talbot
Journal:  J Fam Pract       Date:  1999-01       Impact factor: 0.493

8.  Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile.

Authors:  Gideon Bahar; Raphael Feinmesser; Thomas Shpitzer; Aaron Popovtzer; Rafael M Nagler
Journal:  Cancer       Date:  2007-01-01       Impact factor: 6.860

9.  Salivary transcriptome diagnostics for oral cancer detection.

Authors:  Yang Li; Maie A R St John; Xiaofeng Zhou; Yong Kim; Uttam Sinha; Richard C K Jordan; David Eisele; Elliot Abemayor; David Elashoff; No-Hee Park; David T Wong
Journal:  Clin Cancer Res       Date:  2004-12-15       Impact factor: 12.531

10.  Characterization of RNA in saliva.

Authors:  Noh Jin Park; Yang Li; Tianwei Yu; Brigitta M N Brinkman; David T Wong
Journal:  Clin Chem       Date:  2006-04-06       Impact factor: 8.327

View more
  12 in total

1.  Interictal levels of calcitonin gene related peptide in gingival crevicular fluid of chronic migraine patients.

Authors:  Reza Fekrazad; Ahmadreza Sardarian; Kamran Azma; Masoumeh Karami; Afshin Borhani-Haghighi; Behrouz Gharesi-Fard; Bahram Movahedi
Journal:  Neurol Sci       Date:  2018-04-13       Impact factor: 3.307

2.  Diagnostic efficacy of saliva for dengue - a reality in near future? A piloting initiative.

Authors:  Spoorthi Ravi Banavar; Vidya G S
Journal:  J Clin Diagn Res       Date:  2014-03-15

3.  Need for an Ethical Framework for Testing for Systemic Diseases in Dental Clinics.

Authors:  Marushka Leanne Silveira; Amit Chattopadhyay
Journal:  Ethics Biol Eng Med       Date:  2011-04-01

4.  Gelatin Methacryloyl Microneedle Patches for Minimally Invasive Extraction of Skin Interstitial Fluid.

Authors:  Jixiang Zhu; Xingwu Zhou; Han-Jun Kim; Moyuan Qu; Xing Jiang; KangJu Lee; Li Ren; Qingzhi Wu; Canran Wang; Xunmin Zhu; Peyton Tebon; Shiming Zhang; Junmin Lee; Nureddin Ashammakhi; Samad Ahadian; Mehmet Remzi Dokmeci; Zhen Gu; Wujin Sun; Ali Khademhosseini
Journal:  Small       Date:  2020-02-26       Impact factor: 13.281

5.  Salivary neutrophil sampling feasibility in general population for gene expression analysis.

Authors:  Kenneth Rachlin; Helané Wahbeh; Arnaud Delorme; Dean Radin; Loren Carpenter; Salma Ahmadzai; Serena Valletta; Garret Yount
Journal:  BMC Res Notes       Date:  2022-07-16

Review 6.  A Qualitative Review on the Pharmacokinetics of Antibiotics in Saliva: Implications on Clinical Pharmacokinetic Monitoring in Humans.

Authors:  Tony K L Kiang; Mary H H Ensom
Journal:  Clin Pharmacokinet       Date:  2016-03       Impact factor: 6.447

7.  Multiplexed salivary protein profiling for patients with respiratory diseases using fiber-optic bundles and fluorescent antibody-based microarrays.

Authors:  Shuai Nie; Elena Benito-Peña; Huaibin Zhang; Yue Wu; David R Walt
Journal:  Anal Chem       Date:  2013-09-12       Impact factor: 6.986

8.  Gay and Bisexual Men's Perceptions of the Donation and Use of Human Biological Samples for Research: A Qualitative Study.

Authors:  Chris Patterson; Lisa M McDaid; Shona Hilton
Journal:  PLoS One       Date:  2015-06-08       Impact factor: 3.240

9.  The impact of sample type and procedural attributes on relative acceptability of different colorectal cancer screening regimens.

Authors:  Joanne M Osborne; Ingrid Flight; Carlene J Wilson; Gang Chen; Julie Ratcliffe; Graeme P Young
Journal:  Patient Prefer Adherence       Date:  2018-09-18       Impact factor: 2.711

Review 10.  Revolutionizing Therapeutic Drug Monitoring with the Use of Interstitial Fluid and Microneedles Technology.

Authors:  Tony K L Kiang; Sahan A Ranamukhaarachchi; Mary H H Ensom
Journal:  Pharmaceutics       Date:  2017-10-11       Impact factor: 6.321

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.