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Literature DB >> 18513970

Kinesin-8 molecular motors: putting the brakes on chromosome oscillations.

Melissa K Gardner¹, David J Odde, Kerry Bloom.

Abstract

Recent studies suggest that the human Kinesin-8 molecular motor Kif18A has a role in chromosome congression. Specifically, these studies find that Kif18A promotes chromosome congression by attenuating chromosome oscillation magnitudes. Together with recent modeling work, in vitro studies, and the analysis of in vivo yeast data, these reports reveal how Kinesin-8 molecular motors might control chromosome oscillation amplitudes by spatially regulating the dynamic instability of microtubule plus-ends within the mitotic spindle.

Entities: Gene Species

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Year: 2008 PMID： 18513970 PMCID： PMC2866008 DOI： 10.1016/j.tcb.2008.05.003

Source DB: PubMed Journal: Trends Cell Biol ISSN： 0962-8924 Impact factor: 20.808

25 in total

Review 1. Mitosis: a history of division.

Authors: T J Mitchison; E D Salmon
Journal: Nat Cell Biol Date: 2001-01 Impact factor: 28.824

2. Estimates of lateral and longitudinal bond energies within the microtubule lattice.

Authors: Vincent VanBuren; David J Odde; Lynne Cassimeris
Journal: Proc Natl Acad Sci U S A Date: 2002-04-30 Impact factor: 11.205

3. Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A.

Authors: Miguel Angel Garcia; Nirada Koonrugsa; Takashi Toda
Journal: Curr Biol Date: 2002-04-16 Impact factor: 10.834

4. A simple, mechanistic model for directional instability during mitotic chromosome movements.

Authors: Ajit P Joglekar; Alan J Hunt
Journal: Biophys J Date: 2002-07 Impact factor: 4.033

5. Mechanochemical model of microtubule structure and self-assembly kinetics.

Authors: Vincent VanBuren; Lynne Cassimeris; David J Odde
Journal: Biophys J Date: 2005-06-10 Impact factor: 4.033

6. Dynamic instability of microtubule growth.

Authors: T Mitchison; M Kirschner
Journal: Nature Date: 1984 Nov 15-21 Impact factor: 49.962

7. The Drosophila kinesin-like protein KLP67A is essential for mitotic and male meiotic spindle assembly.

Authors: Rita Gandhi; Silvia Bonaccorsi; Diana Wentworth; Stephen Doxsey; Maurizio Gatti; Andrea Pereira
Journal: Mol Biol Cell Date: 2003-09-17 Impact factor: 4.138

8. Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.

Authors: Robert R West; Terra Malmstrom; J Richard McIntosh
Journal: J Cell Sci Date: 2002-03-01 Impact factor: 5.285

9. Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies.

Authors: R A Walker; E T O'Brien; N K Pryer; M F Soboeiro; W A Voter; H P Erickson; E D Salmon
Journal: J Cell Biol Date: 1988-10 Impact factor: 10.539

10. Drosophila Klp67A is required for proper chromosome congression and segregation during meiosis I.

Authors: Matthew S Savoian; Melanie K Gatt; Maria G Riparbelli; Giuliano Callaini; David M Glover
Journal: J Cell Sci Date: 2004-07-15 Impact factor: 5.285

28 in total

1. Direct regulation of microtubule dynamics by KIF17 motor and tail domains.

Authors: Bipul R Acharya; Cedric Espenel; Geri Kreitzer
Journal: J Biol Chem Date: 2013-09-26 Impact factor: 5.157

Review 2. On and around microtubules: an overview.

Authors: Richard H Wade
Journal: Mol Biotechnol Date: 2009-06-30 Impact factor: 2.695

3. Fission yeast kinesin-8 Klp5 and Klp6 are interdependent for mitotic nuclear retention and required for proper microtubule dynamics.

Authors: Amy Unsworth; Hirohisa Masuda; Susheela Dhut; Takashi Toda
Journal: Mol Biol Cell Date: 2008-09-17 Impact factor: 4.138

Kinesin-8 molecular motors: putting the brakes on chromosome oscillations.

Review 1. Mitosis: a history of division.

2. Estimates of lateral and longitudinal bond energies within the microtubule lattice.

3. Two kinesin-like Kin I family proteins in fission yeast regulate the establishment of metaphase and the onset of anaphase A.

4. A simple, mechanistic model for directional instability during mitotic chromosome movements.

5. Mechanochemical model of microtubule structure and self-assembly kinetics.

6. Dynamic instability of microtubule growth.

7. The Drosophila kinesin-like protein KLP67A is essential for mitotic and male meiotic spindle assembly.

8. Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.

9. Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies.

10. Drosophila Klp67A is required for proper chromosome congression and segregation during meiosis I.

1. Direct regulation of microtubule dynamics by KIF17 motor and tail domains.

Review 2. On and around microtubules: an overview.

3. Fission yeast kinesin-8 Klp5 and Klp6 are interdependent for mitotic nuclear retention and required for proper microtubule dynamics.

4. Kif18A uses a microtubule binding site in the tail for plus-end localization and spindle length regulation.

5. Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8.

6. Analysis and Modeling of Chromosome Congression During Mitosis in the Chemotherapy Drug Cisplatin.

7. Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly.

8. Kinesin-4 KIF21B is a potent microtubule pausing factor.

Review 9. Building complexity: insights into self-organized assembly of microtubule-based architectures.

Review 10. Finding the middle ground: how kinetochores power chromosome congression.