BACKGROUND: The realisation of bariatric surgery has to date modified the digestive process solely through procedures within the abdominal cavity. However, endocrine surgeons have recently demonstrated the feasibility of a minimally invasive approach to the neck. In this study, we explored the feasibility, safety and weight progression of a bariatric procedure performed at the neck. METHODS: Eleven 40-50 kg Yorkshire pigs underwent endoscopic placement of an adjustable band to the cervical esophagus (ECB). Weight was monitored at postoperative days 15, 30, and after 7 weeks; weight progression was compared with an identical group of pigs who underwent a sham procedure. At autopsy, the surgical site was evaluated in a microscopic and macroscopic manner. RESULTS: Mean operating time was 66 +/- 5.76 min. All pigs tolerated the procedure well, except one subject that experienced food intolerance. The ECB group experienced significantly slower weight gain than the sham group (P = 0.005). Proper location of the band and absence of microscopic lesions at the esophageal wall were confirmed at autopsy and pathological examination. CONCLUSION: Bariatric surgery at the neck is feasible and produces effects on weight reduction. Further refinements and longer observation periods are required to propose this procedure as safe and effective alternative in humans.
BACKGROUND: The realisation of bariatric surgery has to date modified the digestive process solely through procedures within the abdominal cavity. However, endocrine surgeons have recently demonstrated the feasibility of a minimally invasive approach to the neck. In this study, we explored the feasibility, safety and weight progression of a bariatric procedure performed at the neck. METHODS: Eleven 40-50 kg Yorkshire pigs underwent endoscopic placement of an adjustable band to the cervical esophagus (ECB). Weight was monitored at postoperative days 15, 30, and after 7 weeks; weight progression was compared with an identical group of pigs who underwent a sham procedure. At autopsy, the surgical site was evaluated in a microscopic and macroscopic manner. RESULTS: Mean operating time was 66 +/- 5.76 min. All pigs tolerated the procedure well, except one subject that experienced food intolerance. The ECB group experienced significantly slower weight gain than the sham group (P = 0.005). Proper location of the band and absence of microscopic lesions at the esophageal wall were confirmed at autopsy and pathological examination. CONCLUSION: Bariatric surgery at the neck is feasible and produces effects on weight reduction. Further refinements and longer observation periods are required to propose this procedure as safe and effective alternative in humans.
Authors: G del Genio; S Tolone; G Rossetti; L Brusciano; F del Genio; F Pizza; F Russo; M Di Martino; V Napolitano; A del Genio Journal: Eur Surg Res Date: 2007-11-20 Impact factor: 1.745
Authors: Gianluca Rossetti; Vincenzo Maffettone; Vincenzo Napolitano; Luigi Brusciano; Gianmattia del Genio; Gianluca Russo; Paolo Limongelli; Francesco Pizza; Maria Di Martino; Salvatore Tolone; Alberto del Genio Journal: Chir Ital Date: 2006 Sep-Oct
Authors: David Nocca; Michel Gagner; Federico Cuenca Abente; Gian Mattia Del Genio; Kazuki Ueda; Ahmad Assalia; Thomas Rogula; Diego Bertani Journal: Obes Surg Date: 2005-04 Impact factor: 4.129
Authors: Helmut G Weiss; Hermann Nehoda; Burkard Labeck; Regina Peer-Kuehberger; Michael Oberwalder; Franz Aigner; Gerold J Wetscher Journal: Obes Surg Date: 2002-08 Impact factor: 4.129
Authors: Gianmattia Del Genio; Michel Gagner; Federico Cuenca-Abente; David Nocca; Laurent Biertho; Federica Del Genio; Ahmad Assalia; Alberto Del Genio Journal: Obes Surg Date: 2008-06-18 Impact factor: 4.129