BACKGROUND: Morbid obesity has become a major global health problem. Surgery remains the only effective treatment for patients with severe obesity, because diet reduction methods and pharmacologic agents have not resulted in long-term weight reduction. Gastric bypass (GBP) can provide adequate weight loss, but after some years, dilatation of the gastric pouch and outlet may lead to weight regain by allowing the patient to increase food intake. METHODS: 2 groups of 6 pigs underwent laparoscopic GBP. In the first group, a non-adjustable silicone band (Proring-band, IOC, Innovative Obesity Care, Saint Etienne, France) was positioned 1 cm proximal to the gastrojejunal anastomosis. In the second group, the device used to stabilize the gastric pouch was an adjustable silicone band (Mid-band, Medical Innovation Developpement, Villeurbanne, France). Weight loss, complications and histological reaction were evaluated after 3 months. RESULTS: Mortality rate was 25% (cardiac arrythmia in 2 pigs). Conversion rate was 25%. The positioning of the band was more difficult with the Mid-band because of its larger size and the presence of the catheter. The average weight change in the Proring group was 15.8 kg (3.5-25.1 kg), and in the Mid-band group was 12.0 kg (6.2-15.1 kg). Morbidity consisted of one intragastric migration of the Proring band into the gastrojejunal anastomosis, and one infection of the port in the Mid-band group treated by removal of the port and antibiotics. CONCLUSION: Use of silicone devices may be safe and effective in the prevention of pouch or outlet dilatation after GBP.
BACKGROUND: Morbid obesity has become a major global health problem. Surgery remains the only effective treatment for patients with severe obesity, because diet reduction methods and pharmacologic agents have not resulted in long-term weight reduction. Gastric bypass (GBP) can provide adequate weight loss, but after some years, dilatation of the gastric pouch and outlet may lead to weight regain by allowing the patient to increase food intake. METHODS: 2 groups of 6 pigs underwent laparoscopic GBP. In the first group, a non-adjustable silicone band (Proring-band, IOC, Innovative Obesity Care, Saint Etienne, France) was positioned 1 cm proximal to the gastrojejunal anastomosis. In the second group, the device used to stabilize the gastric pouch was an adjustable silicone band (Mid-band, Medical Innovation Developpement, Villeurbanne, France). Weight loss, complications and histological reaction were evaluated after 3 months. RESULTS: Mortality rate was 25% (cardiac arrythmia in 2 pigs). Conversion rate was 25%. The positioning of the band was more difficult with the Mid-band because of its larger size and the presence of the catheter. The average weight change in the Proring group was 15.8 kg (3.5-25.1 kg), and in the Mid-band group was 12.0 kg (6.2-15.1 kg). Morbidity consisted of one intragastric migration of the Proring band into the gastrojejunal anastomosis, and one infection of the port in the Mid-band group treated by removal of the port and antibiotics. CONCLUSION: Use of silicone devices may be safe and effective in the prevention of pouch or outlet dilatation after GBP.
Authors: Gianmattia del Genio; Michel Gagner; David Nocca; Federico Cuenca-Abente; Laurent Biertho; Anne Waage; Barbara Faife; Federica del Genio; Camilo Boza; Rajesh Aggarwal; Alberto Del Genio Journal: Obes Surg Date: 2008-05-28 Impact factor: 4.129
Authors: Gianmattia Del Genio; Michel Gagner; Federico Cuenca-Abente; David Nocca; Laurent Biertho; Federica Del Genio; Ahmad Assalia; Alberto Del Genio Journal: Obes Surg Date: 2008-06-18 Impact factor: 4.129
Authors: Malene M Birck; Andreas Vegge; Mikael Støckel; Ismail Gögenur; Thomas Thymann; Karsten P Hammelev; Per T Sangild; Axel K Hansen; Kirsten Raun; Pia von Voss; Thomas Eriksen Journal: Am J Transl Res Date: 2013-09-25 Impact factor: 4.060
Authors: David R Flum; Allison Devlin; Andrew S Wright; Edgar Figueredo; Eric Alyea; Patrick W Hanley; Molly K Lucas; David E Cummings Journal: Obes Surg Date: 2007-10 Impact factor: 4.129