| Literature DB >> 1850043 |
M Equestre1, D Genovese, F Cavalieri, L Fiore, R Santoro, R Perez Bercoff.
Abstract
Complete nucleotide sequencing of the RNAs of two unrelated neurovirulent isolates of Sabin-related poliovirus type 2 revealed that two nucleotides and one amino acid (amino acid 143 in the major capsid protein VP1) consistently departed from the sequences of the nonneurovirulent poliovirus type 2 712 and Sabin vaccine strains. This pattern of mutation appeared to be a feature common to all neurovirulent variants of poliovirus type 2.Entities:
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Year: 1991 PMID: 1850043 PMCID: PMC240633
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103