Literature DB >> 18475987

Transition Metal Ion Complexes of Schiff-bases. Synthesis, Characterization and Antibacterial Properties.

Z H Chohan1, A Munawar, C T Supuran.   

Abstract

Some novel transition metal [Co(II), Cu(II), Ni(II) and Zn(II)] complexes of substituted pyridine Schiff-bases have been prepared and characterized by physical, spectral and analytical data. The synthesized Schiff-bases act as deprotonated tridentate for the complexation reaction with Co(II), Ni(II) and Zn(II) ions. The new compounds, possessing the general formula [M(L)(2)] where [M=Co(II), Cu(II), Ni(II) and Zn(II) and HL=HL(1), HL(2), HL(3) and HL(4)] show an octahedral geometry. In order to evaluate the effect of metal ions upon chelation, the Schiff bases and their complexes have been screened for antibacterial activity against the strains such as Escherichia coli,Staphylococcus aureus, and Pseudomonas aeruginosa. The complexed Schiff bases have shown to be more antibacterial against one more bacterial species as compared to uncomplexed Schiff-bases.

Entities:  

Year:  2001        PMID： 18475987      PMCID： PMC2365267          DOI： 10.1155/MBD.2001.137

Source DB:  PubMed          Journal:  Met Based Drugs        ISSN： 0793-0291


  10 in total

1.  4-(3-Alkyl/benzyl-guanidino)benzenesulfonamides as selective carbonic anhydrase VII inhibitors.

Authors:  Morteza Abdoli; Simone Giovannuzzi; Claudiu T Supuran; Raivis Žalubovskis
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

2.  (Z)-4-{1-[(2-Hy-droxy-ethyl)-amino]-ethyl-idene}-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one.

Authors:  R Jayarajan; P Sharmila; G Jagadeesan; G Vasuki; S Aravindhan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-01-22

3.  Synthesis of New VO(II), Co(II), Ni(II) and Cu(II) Complexes with Isatin-3-Chloro-4-Floroaniline and 2-Pyridinecarboxylidene-4-Aminoantipyrine and their Antimicrobial Studies.

Authors:  Anand P Mishra; Rudra Mishra; Rajendra Jain; Santosh Gupta
Journal:  Mycobiology       Date:  2012-03-31       Impact factor: 1.858

4.  Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors.

Authors:  Morteza Abdoli; Murat Bozdag; Andrea Angeli; Claudiu T Supuran
Journal:  Metabolites       Date:  2018-06-01

5.  Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action.

Authors:  Mehmet Oguz; Erbay Kalay; Suleyman Akocak; Alessio Nocentini; Nebih Lolak; Mehmet Boga; Mustafa Yilmaz; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

6.  Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: synthesis, characterisation and biological evaluation.

Authors:  Jeremie Brichet; Rodrigo Arancibia; Emanuela Berrino; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

7.  7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors.

Authors:  Aleksandrs Pustenko; Alessio Nocentini; Anastasija Balašova; Mikhail Krasavin; Raivis Žalubovskis; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

8.  Spectroscopic Analyses and Antimicrobial Activity of Novel Ciprofloxacin and 7-Hydroxy-4-methylcoumarin, the Plant-Based Natural Benzopyrone Derivative.

Authors:  Mohamed S El-Attar; Sadeek A Sadeek; Sherif M Abd El-Hamid; Hazem S Elshafie
Journal:  Int J Mol Sci       Date:  2022-07-20       Impact factor: 6.208

9.  Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors.

Authors:  Suleyman Akocak; Nabih Lolak; Silvia Bua; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2018-12       Impact factor: 5.051

10.  Phosphonamidates are the first phosphorus-based zinc binding motif to show inhibition of β-class carbonic anhydrases from bacteria, fungi, and protozoa.

Authors:  Siham A Alissa; Hanan A Alghulikah; Zeid A Alothman; Sameh M Osman; Sonia Del Prete; Clemente Capasso; Alessio Nocentini; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051
  10 in total

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