Literature DB >> 18454634

Stem cells: promises versus limitations.

Despoina M Choumerianou1, Helen Dimitriou, Maria Kalmanti.   

Abstract

Stem cells are the self-renewing progenitors of several body tissues and are classified according to their origin and their ability to differentiate. Current research focuses on the potential uses of stem cells in medicine and how they can provide effective treatment for a range of diseases. This approach has resulted in the field of medical practice called regenerative medicine. To attain the promises of regenerative medicine, it is necessary to fully understand the biology and properties of stem cells, achieve their successful differentiation into functional tissues, overcome the barriers related to immune responses after administration, and assess any oncogenic properties that limit their use. The availability of human stem cells not only raises hope for cell replacement therapies, but also provides a system for understanding the mechanisms of embryonic development and disease progression. Nevertheless, it raises ethical concerns that need to be addressed before the use of stem cells in clinical practice.

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Year:  2008        PMID: 18454634     DOI: 10.1089/teb.2007.0216

Source DB:  PubMed          Journal:  Tissue Eng Part B Rev        ISSN: 1937-3368            Impact factor:   6.389


  34 in total

Review 1.  Musculoskeletal tissue engineering with human umbilical cord mesenchymal stromal cells.

Authors:  Limin Wang; Lindsey Ott; Kiran Seshareddy; Mark L Weiss; Michael S Detamore
Journal:  Regen Med       Date:  2011-01       Impact factor: 3.806

Review 2.  [Stem cell therapy and tissue engineering in regenerative urology].

Authors:  M Vaegler; B Amend; W Aicher; A Stenzl; K-D Sievert
Journal:  Urologe A       Date:  2013-12       Impact factor: 0.639

3.  Stem cells to the rescue.

Authors:  Lawrence R Schiller
Journal:  Curr Gastroenterol Rep       Date:  2008-10

4.  Towards a richer debate on tissue engineering: a consideration on the basis of NEST-ethics.

Authors:  A J M Oerlemans; M E C van Hoek; E van Leeuwen; S van der Burg; W J M Dekkers
Journal:  Sci Eng Ethics       Date:  2012-11-15       Impact factor: 3.525

5.  Induction of differentiation by down-regulation of Nanog and Rex-1 in cord blood derived unrestricted somatic stem cells.

Authors:  Lida Langroudi; Mehdi Forouzandeh; Masoud Soleimani; Amir Atashi; Azadeh Fahim Golestaneh
Journal:  Mol Biol Rep       Date:  2013-05-10       Impact factor: 2.316

Review 6.  Microfluidic systems for stem cell-based neural tissue engineering.

Authors:  Mahdi Karimi; Sajad Bahrami; Hamed Mirshekari; Seyed Masoud Moosavi Basri; Amirala Bakhshian Nik; Amir R Aref; Mohsen Akbari; Michael R Hamblin
Journal:  Lab Chip       Date:  2016-07-05       Impact factor: 6.799

Review 7.  From cellular to chemical approach for acute neural and alternative options for age-induced functional diseases.

Authors:  Antonin Bukovsky
Journal:  World J Stem Cells       Date:  2015-09-26       Impact factor: 5.326

Review 8.  Stem cell therapy for voiding and erectile dysfunction.

Authors:  Martin Vaegler; Andrew T Lenis; Lisa Daum; Bastian Amend; Arnulf Stenzl; Patricia Toomey; Markus Renninger; Margot S Damaser; Karl-Dietrich Sievert
Journal:  Nat Rev Urol       Date:  2012-06-19       Impact factor: 14.432

Review 9.  Stem cells in the trabecular meshwork: present and future promises.

Authors:  M J Kelley; A Y Rose; K E Keller; H Hessle; J R Samples; T S Acott
Journal:  Exp Eye Res       Date:  2008-11-18       Impact factor: 3.467

10.  In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfecta.

Authors:  Cristina Panaroni; Roberta Gioia; Anna Lupi; Roberta Besio; Steven A Goldstein; Jaclynn Kreider; Sergey Leikin; Juan Carlos Vera; Edward L Mertz; Egon Perilli; Fabio Baruffaldi; Isabella Villa; Aurora Farina; Marco Casasco; Giuseppe Cetta; Antonio Rossi; Annalisa Frattini; Joan C Marini; Paolo Vezzoni; Antonella Forlino
Journal:  Blood       Date:  2009-05-04       Impact factor: 22.113

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