| Literature DB >> 19061887 |
M J Kelley1, A Y Rose, K E Keller, H Hessle, J R Samples, T S Acott.
Abstract
Primary open-angle glaucoma is recognized as a disease of aging, and studies show a relationship between aging and trabecular meshwork (TM) cell density. Human TM cell division occurs primarily in the anterior, non-filtering region. A commonly used glaucoma treatment, laser trabeculoplasty (LTP), triggers and increases cell division, as well as cell migration of these anterior TM cells. These freshly-divided migrating cells repopulate the burned laser sites, suggesting that they are stem cells. Several studies concerning this putative TM stem cell will be discussed.Entities:
Mesh：
Year: 2008 PMID： 19061887 PMCID： PMC2696933 DOI： 10.1016/j.exer.2008.10.024
Source DB: PubMed Journal: Exp Eye Res ISSN： 0014-4835 Impact factor: 3.467