Literature DB >> 23229374

Towards a richer debate on tissue engineering: a consideration on the basis of NEST-ethics.

A J M Oerlemans1, M E C van Hoek, E van Leeuwen, S van der Burg, W J M Dekkers.   

Abstract

In their 2007 paper, Swierstra and Rip identify characteristic tropes and patterns of moral argumentation in the debate about the ethics of new and emerging science and technologies (or "NEST-ethics"). Taking their NEST-ethics structure as a starting point, we considered the debate about tissue engineering (TE), and argue what aspects we think ought to be a part of a rich and high-quality debate of TE. The debate surrounding TE seems to be predominantly a debate among experts. When considering the NEST-ethics arguments that deal directly with technology, we can generally conclude that consequentialist arguments are by far the most prominently featured in discussions of TE. In addition, many papers discuss principles, rights and duties relevant to aspects of TE, both in a positive and in a critical sense. Justice arguments are only sporadically made, some "good life" arguments are used, others less so (such as the explicit articulation of perceived limits, or the technology as a technological fix for a social problem). Missing topics in the discussion, at least from the perspective of NEST-ethics, are second "level" arguments-those referring to techno-moral change connected to tissue engineering. Currently, the discussion about tissue engineering mostly focuses on its so-called "hard impacts"-quantifiable risks and benefits of the technology. Its "soft impacts"-effects that cannot easily be quantified, such as changes to experience, habits and perceptions, should receive more attention.

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Year:  2012        PMID: 23229374     DOI: 10.1007/s11948-012-9419-y

Source DB:  PubMed          Journal:  Sci Eng Ethics        ISSN: 1353-3452            Impact factor:   3.525


  84 in total

1.  Biomedical, ethical, and moral issues being forced by advanced medical technologies.

Authors:  Richard M Satava
Journal:  Proc Am Philos Soc       Date:  2003-09

Review 2.  An overview of stem cell research and regulatory issues.

Authors:  Christopher R Cogle; Steven M Guthrie; Ronald C Sanders; William L Allen; Edward W Scott; Bryon E Petersen
Journal:  Mayo Clin Proc       Date:  2003-08       Impact factor: 7.616

Review 3.  Legal and ethical status of stem cells as medicinal products.

Authors:  Lincoln Tsang
Journal:  Adv Drug Deliv Rev       Date:  2005-11-16       Impact factor: 15.470

4.  An in vitro approach to assess the toxicity of inhaled tobacco smoke components: nicotine, cadmium, formaldehyde and urethane.

Authors:  Dominique Balharry; Keith Sexton; Kelly A BéruBé
Journal:  Toxicology       Date:  2007-11-09       Impact factor: 4.221

Review 5.  Endothelial stem cells and precursors for tissue engineering: cell source, differentiation, selection, and application.

Authors:  Saejeong Kim; Horst von Recum
Journal:  Tissue Eng Part B Rev       Date:  2008-03       Impact factor: 6.389

6.  Banking together. A unified model of informed consent for biobanking.

Authors:  Elena Salvaterra; Lucilla Lecchi; Silvia Giovanelli; Barbara Butti; Maria Teresa Bardella; Pier Alberto Bertazzi; Silvano Bosari; Guido Coggi; Domenico A Coviello; Faustina Lalatta; Maurizio Moggio; Mario Nosotti; Alberto Zanella; Paolo Rebulla
Journal:  EMBO Rep       Date:  2008-04       Impact factor: 8.807

Review 7.  Tissue engineering.

Authors:  R Langer; J P Vacanti
Journal:  Science       Date:  1993-05-14       Impact factor: 47.728

8.  Informing participants in clinical trials with ex vivo human tissue-engineered products: what to tell and how to tell it?

Authors:  Leen Trommelmans; Joseph Selling; Kris Dierickx
Journal:  J Tissue Eng Regen Med       Date:  2008-06       Impact factor: 3.963

9.  Ethical reflections on clinical trials with human tissue engineered products.

Authors:  L Trommelmans; J Selling; K Dierickx
Journal:  J Med Ethics       Date:  2008-09       Impact factor: 2.903

10.  Tissue engineering: current strategies and future directions.

Authors:  Jennifer L Olson; Anthony Atala; James J Yoo
Journal:  Chonnam Med J       Date:  2011-04-26
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  3 in total

Review 1.  Ethical considerations in the translation of regenerative biofabrication technologies into clinic and society.

Authors:  I A Otto; C C Breugem; J Malda; A L Bredenoord
Journal:  Biofabrication       Date:  2016-10-07       Impact factor: 9.954

2.  Craniofacial stem cell therapy: New light at the end of the tunnel.

Authors:  S M Balaji
Journal:  Ann Maxillofac Surg       Date:  2014-01

3.  A Lay Ethics Quest for Technological Futures: About Tradition, Narrative and Decision-Making.

Authors:  Simone van der Burg
Journal:  Nanoethics       Date:  2016-08-17       Impact factor: 0.917

  3 in total

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