Literature DB >> 18443750

Genetics of the human renin angiotensin system.

Xavier Jeunemaitre1.   

Abstract

The genes coding for the renin angiotensin system have been extensively studied. During the last 15 years, informative markers and functional polymorphisms have been identified, and numerous linkage and association studies have been performed in cardiovascular diseases, especially human hypertension. This mini-review aims to summarize the main findings observed for each component of this enzymatic cascade taken alone or in combination, with an emphasis on the most recent or innovative studies.

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Year:  2008        PMID： 18443750     DOI： 10.1007/s00109-008-0344-0

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  33 in total

Review 1.  Human genetics, animal models and computer simulations for studying hypertension.

Authors:  Nobuyuki Takahashi; Oliver Smithies
Journal:  Trends Genet       Date:  2004-03       Impact factor: 11.639

Review 2.  Angiotensinogen variants and human hypertension.

Authors:  X Jeunemaitre; A P Gimenez-Roqueplo; J Célérier; P Corvol
Journal:  Curr Hypertens Rep       Date:  1999 Feb-Mar       Impact factor: 5.369

Review 3.  Angiotensin II receptor polymorphisms in hypertension. Pharmacogenomic considerations.

Authors:  Bruno Baudin
Journal:  Pharmacogenomics       Date:  2002-01       Impact factor: 2.533

4.  Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure.

Authors:  X Zhu; N Bouzekri; L Southam; R S Cooper; A Adeyemo; C A McKenzie; A Luke; G Chen; R C Elston; R Ward
Journal:  Am J Hum Genet       Date:  2001-03-27       Impact factor: 11.025

Review 5.  Polymorphism in angiotensin II receptor genes and hypertension.

Authors:  Bruno Baudin
Journal:  Exp Physiol       Date:  2005-01-07       Impact factor: 2.969

6.  The M235T polymorphism in the angiotensinogen gene is associated with the risk of malignant hypertension in white patients.

Authors:  Bert-Jan H van den Born; Gert A van Montfrans; Andre G Uitterlinden; Aeilko H Zwinderman; Richard P Koopmans
Journal:  J Hypertens       Date:  2007-11       Impact factor: 4.844

7.  Sequence variation in the human angiotensin converting enzyme.

Authors:  M J Rieder; S L Taylor; A G Clark; D A Nickerson
Journal:  Nat Genet       Date:  1999-05       Impact factor: 38.330

8.  Genetic determinants of nonmodulating hypertension.

Authors:  Natapong Kosachunhanun; Steven C Hunt; Paul N Hopkins; Roger R Williams; Xavier Jeunemaitre; Pierre Corvol; Claudio Ferri; Richard M Mortensen; Norman K Hollenberg; Gordon H Williams
Journal:  Hypertension       Date:  2003-10-06       Impact factor: 10.190

9.  Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations.

Authors:  Samy Hadjadj; Lise Tarnow; Carol Forsblom; Gbenga Kazeem; Michel Marre; Per-Henrik Groop; Hans-Henrik Parving; François Cambien; David A Tregouet; Ivo G Gut; Alexandre Théva; Dominique Gauguier; Martin Farrall; Roger Cox; Fumihiko Matsuda; Mark Lathrop; Nathalie Hager-Vionnet
Journal:  J Am Soc Nephrol       Date:  2007-03-21       Impact factor: 10.121

10.  Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.

Authors:  Daniel Levy; Martin G Larson; Emelia J Benjamin; Christopher Newton-Cheh; Thomas J Wang; Shih-Jen Hwang; Ramachandran S Vasan; Gary F Mitchell
Journal:  BMC Med Genet       Date:  2007-09-19       Impact factor: 2.103
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  15 in total

1.  RAAS and adrenergic genes in heart failure: Function, predisposition and survival implications.

Authors:  Alberto J Alves; Nir Eynon; José Oliveira; Ehud Goldhammer
Journal:  World J Cardiol       Date:  2010-07-26

Review 2.  Systems biology and heart failure: concepts, methods, and potential research applications.

Authors:  Kirkwood F Adams
Journal:  Heart Fail Rev       Date:  2010-07       Impact factor: 4.214

3.  Linkage of angiotensinogen gene polymorphisms with hypertension in a sibling study of Hong Kong Chinese.

Authors:  Yu-Jing Fang; Han-Bing Deng; G Neil Thomas; Chi H Tzang; Cai-Xia Li; Zong-Li Xu; Mengsu Yang; Brian Tomlinson
Journal:  J Hypertens       Date:  2010-06       Impact factor: 4.844

4.  Do ACE (rs4646994) and αADDUCIN (rs4961) gene polymorphisms predict the recurrence of hypertensive intracerebral hemorrhage?

Authors:  Usha K Misra; Jayantee Kalita; Bindu I Somarajan; Bishwanath Kumar; Moromi Das; Balraj Mittal
Journal:  Neurol Sci       Date:  2011-12-24       Impact factor: 3.307

5.  Implications of the angiotensin converting enzyme gene insertion/deletion polymorphism in health and disease: a snapshot review.

Authors:  Paul R Gard
Journal:  Int J Mol Epidemiol Genet       Date:  2010-03-20

Review 6.  The renin-angiotensin system and cancer: old dog, new tricks.

Authors:  Amee J George; Walter G Thomas; Ross D Hannan
Journal:  Nat Rev Cancer       Date:  2010-10-22       Impact factor: 60.716

Review 7.  Efficiency and specificity of RAAS inhibitors in cardiovascular diseases: how to achieve better end-organ protection?

Authors:  Ali Nehme; Kazem Zibara
Journal:  Hypertens Res       Date:  2017-07-06       Impact factor: 3.872

8.  Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: the importance of haplotypes.

Authors:  W Scott Watkins; Steven C Hunt; Gordon H Williams; Whitney Tolpinrud; Xavier Jeunemaitre; Jean-Marc Lalouel; Lynn B Jorde
Journal:  J Hypertens       Date:  2010-01       Impact factor: 4.844

Review 9.  Genetics of hypertension: from experimental animals to humans.

Authors:  Christian Delles; Martin W McBride; Delyth Graham; Sandosh Padmanabhan; Anna F Dominiczak
Journal:  Biochim Biophys Acta       Date:  2009-12-24

10.  Gene Polymorphisms of the Renin-Angiotensin-Aldosterone System as Risk Factors for the Development of In-Stent Restenosis in Patients with Stable Coronary Artery Disease.

Authors:  Madina Azova; Kalima Timizheva; Amira Ait Aissa; Mikhail Blagonravov; Olga Gigani; Anna Aghajanyan; Leyla Tskhovrebova
Journal:  Biomolecules       Date:  2021-05-20
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