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Literature DB >> 18440794

Mechanisms involved in the regulation of histone lysine demethylases.

Fei Lan¹, Amanda Clair Nottke, Yang Shi.

Abstract

Since the first histone lysine demethylase KDM1 (LSD1) was discovered in 2004, a great number of histone demethylases have been recognized and shown to play important roles in gene expression, as well as cellular differentiation and animal development. The chemical mechanisms and substrate specificities have already been extensively discussed elsewhere. This review focuses primarily on regulatory mechanisms that modulate demethylase recruitment and activity.

Entities: Gene

Mesh：

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Year: 2008 PMID： 18440794 PMCID： PMC2674377 DOI： 10.1016/j.ceb.2008.03.004

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

68 in total

1. CoREST is an integral component of the CoREST- human histone deacetylase complex.

Authors: A You; J K Tong; C M Grozinger; S L Schreiber
Journal: Proc Natl Acad Sci U S A Date: 2001-02-13 Impact factor: 11.205

2. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells.

Authors: Yuin-Han Loh; Weiwei Zhang; Xi Chen; Joshy George; Huck-Hui Ng
Journal: Genes Dev Date: 2007-10-15 Impact factor: 11.361

3. Opposing LSD1 complexes function in developmental gene activation and repression programmes.

Authors: Jianxun Wang; Kathleen Scully; Xiaoyan Zhu; Ling Cai; Jie Zhang; Gratien G Prefontaine; Anna Krones; Kenneth A Ohgi; Ping Zhu; Ivan Garcia-Bassets; Forrest Liu; Havilah Taylor; Jean Lozach; Friederike L Jayes; Kenneth S Korach; Christopher K Glass; Xiang-Dong Fu; Michael G Rosenfeld
Journal: Nature Date: 2007-03-28 Impact factor: 49.962

4. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

Authors: Karl Agger; Paul A C Cloos; Jesper Christensen; Diego Pasini; Simon Rose; Juri Rappsilber; Irina Issaeva; Eli Canaani; Anna Elisabetta Salcini; Kristian Helin
Journal: Nature Date: 2007-08-22 Impact factor: 49.962

5. A histone H3 lysine 27 demethylase regulates animal posterior development.

Authors: Fei Lan; Peter E Bayliss; John L Rinn; Johnathan R Whetstine; Jordon K Wang; Shuzhen Chen; Shigeki Iwase; Roman Alpatov; Irina Issaeva; Eli Canaani; Thomas M Roberts; Howard Y Chang; Yang Shi
Journal: Nature Date: 2007-09-12 Impact factor: 49.962

6. Large-scale analysis of the human and mouse transcriptomes.

Authors: Andrew I Su; Michael P Cooke; Keith A Ching; Yaron Hakak; John R Walker; Tim Wiltshire; Anthony P Orth; Raquel G Vega; Lisa M Sapinoso; Aziz Moqrich; Ardem Patapoutian; Garret M Hampton; Peter G Schultz; John B Hogenesch
Journal: Proc Natl Acad Sci U S A Date: 2002-03-19 Impact factor: 11.205

7. Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.

Authors: Thomas Rudolph; Masato Yonezawa; Sandro Lein; Kathleen Heidrich; Stefan Kubicek; Christiane Schäfer; Sameer Phalke; Matthias Walther; Andreas Schmidt; Thomas Jenuwein; Gunter Reuter
Journal: Mol Cell Date: 2007-04-13 Impact factor: 17.970

8. Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence.

Authors: J J M Cowger; Q Zhao; M Isovic; J Torchia
Journal: Oncogene Date: 2006-11-27 Impact factor: 9.867

9. Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

Authors: Min Gyu Lee; Raffaella Villa; Patrick Trojer; Jessica Norman; Kai-Ping Yan; Danny Reinberg; Luciano Di Croce; Ramin Shiekhattar
Journal: Science Date: 2007-08-30 Impact factor: 47.728

10. Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development.

Authors: Luisa Di Stefano; Jun-Yuan Ji; Nam-Sung Moon; Anabel Herr; Nicholas Dyson
Journal: Curr Biol Date: 2007-05-01 Impact factor: 10.834

110 in total

1. Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

Authors: Nikita Avvakumov; Marie-Eve Lalonde; Nehmé Saksouk; Eric Paquet; Karen C Glass; Anne-Julie Landry; Yannick Doyon; Christelle Cayrou; Geneviève A Robitaille; Darren E Richard; Xiang-Jiao Yang; Tatiana G Kutateladze; Jacques Côté
Journal: Mol Cell Biol Date: 2011-12-05 Impact factor: 4.272

Mechanisms involved in the regulation of histone lysine demethylases.

1. CoREST is an integral component of the CoREST- human histone deacetylase complex.

2. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells.

3. Opposing LSD1 complexes function in developmental gene activation and repression programmes.

4. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

5. A histone H3 lysine 27 demethylase regulates animal posterior development.

6. Large-scale analysis of the human and mouse transcriptomes.

7. Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.

8. Biochemical characterization of the zinc-finger protein 217 transcriptional repressor complex: identification of a ZNF217 consensus recognition sequence.

9. Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

10. Mutation of Drosophila Lsd1 disrupts H3-K4 methylation, resulting in tissue-specific defects during development.

1. Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.

2. Histone demethylase LSD1 is a folate-binding protein.

Review 3. Histone methylation in myelodysplastic syndromes.

4. Interaction of JMJD6 with single-stranded RNA.

5. Evolution and conservation of JmjC domain proteins in the green lineage.

6. Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining.

7. Profiling RE1/REST-mediated histone modifications in the human genome.

Review 8. Developmental roles of the histone lysine demethylases.

Review 9. Role of chromatin states in transcriptional memory.

Review 10. PELP1: A novel therapeutic target for hormonal cancers.