| Literature DB >> 18428746 |
Erol E Gulcicek1, Christopher M Colangelo, Walter McMurray, Kathryn Stone, Kenneth Williams, Terence Wu, Hongyu Zhao, Heidi Spratt, Alexander Kurosky, Baolin Wu.
Abstract
In recent years, several proteomic methodologies have been developed that now make it possible to identify, characterize, and comparatively quantify the relative level of expression of hundreds of proteins that are coexpressed in a given cell type or tissue, or that are found in biological fluids such as serum. These advances have resulted from the integration of diverse scientific disciplines including molecular and cellular biology, protein/peptide chemistry, bioinformatics, analytical and bioanalytical chemistry, and the use of instrumental and software tools such as multidimensional electrophoretic and chromatographic separations and mass spectrometry. In this unit, some of the common protein-profiling technologies are reviewed, along with the accompanying data-analysis tools.Mesh：
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Year: 2005 PMID： 18428746 PMCID： PMC3863626 DOI： 10.1002/0471250953.bi1301s10
Source DB: PubMed Journal: Curr Protoc Bioinformatics ISSN： 1934-3396