Literature DB >> 18400971

Enhancement of diagnostic efficiency by a gamma interferon release assay for pulmonary tuberculosis.

Kelly Aparecida Kanunfre1, Olavo Henrique Munhoz Leite, Max Igor Lopes, Marcelo Litvoc, Antonio Walter Ferreira.   

Abstract

This study was designed to examine the use of the QuantiFERON-TB Gold assay as an aid in the diagnosis of active pulmonary tuberculosis (TB) in Brazilian patients. Using the receiver operating characteristic curve, the cutoff was adjusted to >or=0.20 IU/ml. The sensitivity increased to 86%, with 100% specificity. All TB patients with negative sputum smear microscopy and negative culture results were positive using this test.

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Year:  2008        PMID： 18400971      PMCID： PMC2446630          DOI： 10.1128/CVI.00026-08

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


  11 in total

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