Literature DB >> 18396450

Nutritional control via Tor signaling in Saccharomyces cerevisiae.

John R Rohde1, Robert Bastidas, Rekha Puria, Maria E Cardenas.   

Abstract

The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.

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Year:  2008        PMID: 18396450      PMCID: PMC2394285          DOI: 10.1016/j.mib.2008.02.013

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN: 1369-5274            Impact factor:   7.934


  57 in total

1.  Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression.

Authors:  Rosa M Marion; Aviv Regev; Eran Segal; Yoseph Barash; Daphne Koller; Nir Friedman; Erin K O'Shea
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-07       Impact factor: 11.205

2.  Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.

Authors:  Hong Li; Chi Kwan Tsang; Marcus Watkins; Paula G Bertram; X F Steven Zheng
Journal:  Nature       Date:  2006-08-09       Impact factor: 49.962

3.  RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1.

Authors:  P E Burnett; R K Barrow; N A Cohen; S H Snyder; D M Sabatini
Journal:  Proc Natl Acad Sci U S A       Date:  1998-02-17       Impact factor: 11.205

4.  Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.

Authors:  Michael W Xie; Fulai Jin; Heejun Hwang; Seungmin Hwang; Vikram Anand; Mara C Duncan; Jing Huang
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-09       Impact factor: 11.205

5.  Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.

Authors:  Yoshiaki Kamada; Yuko Fujioka; Nobuo N Suzuki; Fuyuhiko Inagaki; Stephan Wullschleger; Robbie Loewith; Michael N Hall; Yoshinori Ohsumi
Journal:  Mol Cell Biol       Date:  2005-08       Impact factor: 4.272

6.  The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.

Authors:  Alexes Daquinag; Maria Fadri; Sung Yun Jung; Jun Qin; Jeannette Kunz
Journal:  Mol Cell Biol       Date:  2006-11-13       Impact factor: 4.272

7.  Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway.

Authors:  Amy K A deHart; Joshua D Schnell; Damian A Allen; Ju-Yun Tsai; Linda Hicke
Journal:  Mol Biol Cell       Date:  2003-11       Impact factor: 4.138

8.  mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability.

Authors:  Christine Mayer; Jian Zhao; Xuejun Yuan; Ingrid Grummt
Journal:  Genes Dev       Date:  2004-02-15       Impact factor: 11.361

9.  A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size.

Authors:  Paul Jorgensen; Ivan Rupes; Jeffrey R Sharom; Lisa Schneper; James R Broach; Mike Tyers
Journal:  Genes Dev       Date:  2004-10-01       Impact factor: 11.361

10.  TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors.

Authors:  John R Rohde; Susan Campbell; Sara A Zurita-Martinez; N Shane Cutler; Mark Ashe; Maria E Cardenas
Journal:  Mol Cell Biol       Date:  2004-10       Impact factor: 4.272

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  56 in total

Review 1.  Staying alive: metabolic adaptations to quiescence.

Authors:  James R Valcourt; Johanna M S Lemons; Erin M Haley; Mina Kojima; Olukunle O Demuren; Hilary A Coller
Journal:  Cell Cycle       Date:  2012-05-01       Impact factor: 4.534

2.  Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae.

Authors:  Vidhya Ramachandran; Paul K Herman
Journal:  Genetics       Date:  2010-11-15       Impact factor: 4.562

3.  Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom.

Authors:  Cecelia A Shertz; Robert J Bastidas; Wenjun Li; Joseph Heitman; Maria E Cardenas
Journal:  BMC Genomics       Date:  2010-09-23       Impact factor: 3.969

Review 4.  Transcriptional regulation in yeast during diauxic shift and stationary phase.

Authors:  Luciano Galdieri; Swati Mehrotra; Sean Yu; Ales Vancura
Journal:  OMICS       Date:  2010-09-23

5.  Plasma membrane recruitment and activation of the AGC kinase Ypk1 is mediated by target of rapamycin complex 2 (TORC2) and its effector proteins Slm1 and Slm2.

Authors:  Brad J Niles; Huzefa Mogri; Andrew Hill; Ariadne Vlahakis; Ted Powers
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-17       Impact factor: 11.205

6.  A VAST staging area for regulatory proteins.

Authors:  Aaron P Mitchell
Journal:  Proc Natl Acad Sci U S A       Date:  2008-05-12       Impact factor: 11.205

Review 7.  Signaling cascades as drug targets in model and pathogenic fungi.

Authors:  Robert J Bastidas; Jennifer L Reedy; Helena Morales-Johansson; Joseph Heitman; Maria E Cardenas
Journal:  Curr Opin Investig Drugs       Date:  2008-08

Review 8.  Regulations of sugar transporters: insights from yeast.

Authors:  J Horák
Journal:  Curr Genet       Date:  2013-03-01       Impact factor: 3.886

9.  Regulation and function of yeast PAS kinase: a role in the maintenance of cellular integrity.

Authors:  Julianne H Grose; Eleanor Sundwall; Jared Rutter
Journal:  Cell Cycle       Date:  2009-06-20       Impact factor: 4.534

Review 10.  Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae.

Authors:  Bart Smets; Ruben Ghillebert; Pepijn De Snijder; Matteo Binda; Erwin Swinnen; Claudio De Virgilio; Joris Winderickx
Journal:  Curr Genet       Date:  2010-02       Impact factor: 3.886

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