Literature DB >> 1839356

The treatment of hypertension: new lamps for old?

J R Hampton1.   

Abstract

Meta-analysis of clinical trials does not help the clinician to treat individual patients. A general conclusion that the reduction of high blood pressure is beneficial has to be matched by specific information about the level of blood pressure that is acceptable and about the effect of particular doses of specific drugs. Results obtained from trials of "old-fashioned" antihypertensive drugs cannot confidently be extrapolated to "modern" agents. Sufficient data do not exist to encourage universal drug treatment for patients with "mild" hypertension.

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Year:  1991        PMID: 1839356     DOI: 10.1007/bf00143524

Source DB:  PubMed          Journal:  Cardiovasc Drugs Ther        ISSN: 0920-3206            Impact factor:   3.727


  21 in total

1.  Symptoms of low blood pressure: a population study.

Authors:  S Wessely; J Nickson; B Cox
Journal:  BMJ       Date:  1990 Aug 18-25

2.  The case for low dose diuretics in hypertension: comparison of low and conventional doses of cyclopenthiazide.

Authors:  G McVeigh; D Galloway; D Johnston
Journal:  BMJ       Date:  1988-07-09

3.  MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1985-07-13

4.  Cuff and ambulatory blood pressure in subjects with essential hypertension.

Authors:  J S Floras; J V Jones; M O Hassan; B Osikowska; P S Sever; P Sleight
Journal:  Lancet       Date:  1981-07-18       Impact factor: 79.321

5.  Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.

Authors: 
Journal:  Lancet       Date:  1981-09-12       Impact factor: 79.321

6.  Benefits and potential harm of lowering high blood pressure.

Authors:  J M Cruickshank; J M Thorp; F J Zacharias
Journal:  Lancet       Date:  1987-03-14       Impact factor: 79.321

7.  Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. Intersalt Cooperative Research Group.

Authors: 
Journal:  BMJ       Date:  1988-07-30

8.  Is exercise good for high blood pressure?

Authors:  R G Wilcox; T Bennett; A M Brown; I A Macdonald
Journal:  Br Med J (Clin Res Ed)       Date:  1982-09-18

9.  Prevention of atherosclerotic complications: controlled trial of ketanserin. Prevention of Atherosclerotic Complications with Ketanserin Trial Group.

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Journal:  BMJ       Date:  1989-02-18

Review 10.  Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context.

Authors:  R Collins; R Peto; S MacMahon; P Hebert; N H Fiebach; K A Eberlein; J Godwin; N Qizilbash; J O Taylor; C H Hennekens
Journal:  Lancet       Date:  1990-04-07       Impact factor: 79.321

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  1 in total

Review 1.  Treatment of hypertension in the elderly--what have we learned from the recent trials?

Authors:  P Lund-Johansen
Journal:  Cardiovasc Drugs Ther       Date:  1992-12       Impact factor: 3.727

  1 in total

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