Christopher G Lis1, Digant Gupta, James F Grutsch. 1. Cancer Treatment Centers of America, Midwestern Regional Medical Center, Zion, IL 60099, USA. christopher.lis@ctca-hope.com
Abstract
GOALS: Anorexia is the second most common symptom after fatigue in patients with advanced cancer. We quantified the relationship between anorexia and patient satisfaction with quality of life (QoL) in advanced cancer. MATERIALS AND METHODS: A case series of 954 cancer patients treated at the Cancer Treatment Centers of America. Anorexia was measured using the QLQ-C30 loss of appetite/anorexia subscale. Patient satisfaction with QoL was measured using the Ferrans and Powers Quality of Life Index (QLI). The relationship between anorexia and QLI was evaluated using multivariate analysis of variance and multiple regression analysis. MAIN RESULTS: Of 954 patients, 579 were females and 375 males with the median age at presentation of 56 years. Of these patients, 66% had failed prior treatment. Most common cancers were breast (26%), colorectal (19%), and lung (16%). After controlling for the effects of age, treatment history, and other QLQ-C30 symptom subscales, every 10 unit increase in anorexia was statistically significantly associated with 0.18 unit decline in QLI health and physical function score. CONCLUSION: We found that anorexia is significantly correlated with patient satisfaction with health and physical function in advanced cancer. Future studies should evaluate the impact of integrative cancer care services on patient satisfaction with QoL.
GOALS: Anorexia is the second most common symptom after fatigue in patients with advanced cancer. We quantified the relationship between anorexia and patient satisfaction with quality of life (QoL) in advanced cancer. MATERIALS AND METHODS: A case series of 954 cancerpatients treated at the Cancer Treatment Centers of America. Anorexia was measured using the QLQ-C30 loss of appetite/anorexia subscale. Patient satisfaction with QoL was measured using the Ferrans and Powers Quality of Life Index (QLI). The relationship between anorexia and QLI was evaluated using multivariate analysis of variance and multiple regression analysis. MAIN RESULTS: Of 954 patients, 579 were females and 375 males with the median age at presentation of 56 years. Of these patients, 66% had failed prior treatment. Most common cancers were breast (26%), colorectal (19%), and lung (16%). After controlling for the effects of age, treatment history, and other QLQ-C30 symptom subscales, every 10 unit increase in anorexia was statistically significantly associated with 0.18 unit decline in QLI health and physical function score. CONCLUSION: We found that anorexia is significantly correlated with patient satisfaction with health and physical function in advanced cancer. Future studies should evaluate the impact of integrative cancer care services on patient satisfaction with QoL.
Authors: M Pirovano; M Maltoni; O Nanni; M Marinari; M Indelli; G Zaninetta; V Petrella; S Barni; E Zecca; E Scarpi; R Labianca; D Amadori; G Luporini Journal: J Pain Symptom Manage Date: 1999-04 Impact factor: 3.612
Authors: Charlotte Goodrose-Flores; Stephanie Bonn; Caritha Klasson; Maria Helde Frankling; Ylva Trolle Lagerros; Linda Björkhem-Bergman Journal: Life (Basel) Date: 2022-04-30
Authors: S Culine; C Chambrier; A Tadmouri; P Senesse; P Seys; A Radji; M Rotarski; A Balian; P Dufour Journal: Support Care Cancer Date: 2014-02-21 Impact factor: 3.603
Authors: Tora S Solheim; Peter M Fayers; Torill Fladvad; Ben Tan; Frank Skorpen; Kenneth Fearon; Vickie E Baracos; Pål Klepstad; Florian Strasser; Stein Kaasa Journal: J Cachexia Sarcopenia Muscle Date: 2012-04-26 Impact factor: 12.910
Authors: S Blauwhoff-Buskermolen; C Ruijgrok; R W Ostelo; H C W de Vet; H M W Verheul; M A E de van der Schueren; J A E Langius Journal: Support Care Cancer Date: 2015-07-10 Impact factor: 3.603
Authors: Matthew A Carson; Joanne Reid; Loreena Hill; Lana Dixon; Patrick Donnelly; Paul Slater; Alyson Hill; Donna Fitzsimons Journal: BMC Palliat Care Date: 2019-10-20 Impact factor: 3.234