Literature DB >> 18376172

Prediction of mortality and of the need for massive transfusion in casualties arriving at combat support hospitals in Iraq.

Leopoldo C Cancio1, Charles E Wade, Susan A West, John B Holcomb.   

Abstract

BACKGROUND: Our purpose was to compare the Revised Trauma Score (RTS) with the new Field Triage Score (FTS) for prediction of mortality (MORT) and of need for massive transfusion (MASS, >or=10 units of packed cells or whole blood) in casualties arriving at combat support hospitals in Iraq.
METHODS: Six hundred ninety-two cases were reviewed; 536 had complete data and were included. Total Glasgow Coma Scale score (GCS total) not GCS motor was used. Thus, a modification (FTS 07) of the FTS was calculated, using GCS <8 and systolic arterial pressure (SAP) <100 as cut-points, with range 0 to 2. Variables different by univariate analysis underwent logistic regression analysis (LRA) and areas under the curve for receiver operating characteristic curves (AUC) were calculated. By LRA, probability of an outcome is given by p = e(k)/(1 + e(k)).
RESULTS: By LRA for MORT, k = 0.616 - 0.438 x RTS; AUC = 0.708. When used instead of RTS, FTS 07 provided k = -0.716 - 1.009 x FTS 07; AUC = 0.687 (NS). For MASS, k = 0.638 - 0.115 x RTS - 0.011 x DAP + 0.358 x SI, where DAP is diastolic arterial pressure and SI is shock index, i.e., heart rate or SAP; AUC = 0.638. When used instead of RTS, FTS 07 provided k = -0.740 - 0.376 x FTS 07- 0.011 x DAP; AUC = 0.618 (NS).
CONCLUSIONS: RTS emerged as the best predictor of MORT, with FTS 07 a close surrogate. This indicates the effect of impaired mentation on MORT in these data. For prediction of MASS, RTS as well as the heart rate and blood pressure predominated. The advantage of FTS 07 (or original FTS) over RTS is the former's ease of computation.

Entities:  

Mesh:

Year:  2008        PMID: 18376172     DOI: 10.1097/TA.0b013e3181608c21

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  17 in total

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Authors:  E Guerado; A Medina; M I Mata; J M Galvan; M L Bertrand
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2.  A high fresh frozen plasma: packed red blood cell transfusion ratio decreases mortality in all massively transfused trauma patients regardless of admission international normalized ratio.

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Journal:  J Trauma       Date:  2011-08

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9.  The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks.

Authors:  John B Holcomb; Deborah J del Junco; Erin E Fox; Charles E Wade; Mitchell J Cohen; Martin A Schreiber; Louis H Alarcon; Yu Bai; Karen J Brasel; Eileen M Bulger; Bryan A Cotton; Nena Matijevic; Peter Muskat; John G Myers; Herb A Phelan; Christopher E White; Jiajie Zhang; Mohammad H Rahbar
Journal:  JAMA Surg       Date:  2013-02       Impact factor: 14.766

10.  A Multiscale Deep Learning Method for Quantitative Visualization of Traumatic Hemoperitoneum at CT: Assessment of Feasibility and Comparison with Subjective Categorical Estimation.

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