Literature DB >> 18366968

Genomics and proteomics in renal cell carcinoma: diagnosis, prognosis, and treatment selection.

Jon Jones1, Allan J Pantuck.   

Abstract

The term renal cell carcinoma (RCC) once referred to a single entity but now encompasses a spectrum of diverse epithelial tumors with a common derivation from the renal tubular epithelium. The variable course of RCC remains problematic for patient management, despite advances in diagnosis and improved understanding of prognostic factors. However, powerful, high-throughput technologies that now analyze the entire genome and proteome promise to elucidate the heterogeneity of this disease and eventually enable a patient-tailored, individualized medicine. This review considers the clinical relevance and general significance of gene expression and protein-profiling studies.

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Year:  2008        PMID： 18366968     DOI： 10.1007/s11934-008-0004-5

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN： 1527-2737            Impact factor:   3.092


  43 in total

1.  Gene expression profiling of clear cell renal cell carcinoma: gene identification and prognostic classification.

Authors:  M Takahashi; D R Rhodes; K A Furge; H Kanayama ; S Kagawa; B B Haab; B T Teh
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-07       Impact factor: 11.205

2.  A molecular signature of metastasis in primary solid tumors.

Authors:  Sridhar Ramaswamy; Ken N Ross; Eric S Lander; Todd R Golub
Journal:  Nat Genet       Date:  2002-12-09       Impact factor: 38.330

Review 3.  Clinical proteomics: translating benchside promise into bedside reality.

Authors:  Emanuel F Petricoin; Kathryn C Zoon; Elise C Kohn; J Carl Barrett; Lance A Liotta
Journal:  Nat Rev Drug Discov       Date:  2002-09       Impact factor: 84.694

4.  Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.

Authors:  Robert J Motzer; Thomas E Hutson; Piotr Tomczak; M Dror Michaelson; Ronald M Bukowski; Olivier Rixe; Stéphane Oudard; Sylvie Negrier; Cezary Szczylik; Sindy T Kim; Isan Chen; Paul W Bycott; Charles M Baum; Robert A Figlin
Journal:  N Engl J Med       Date:  2007-01-11       Impact factor: 91.245

5.  Identification and classification of differentially expressed genes in renal cell carcinoma by expression profiling on a global human 31,500-element cDNA array.

Authors:  J M Boer; W K Huber; H Sültmann; F Wilmer; A von Heydebreck; S Haas; B Korn; B Gunawan; A Vente; L Füzesi; M Vingron; A Poustka
Journal:  Genome Res       Date:  2001-11       Impact factor: 9.043

6.  Clear cell renal cell carcinoma: gene expression analyses identify a potential signature for tumor aggressiveness.

Authors:  Farhad Kosari; Alexander S Parker; Dagmar Marie Kube; Christine M Lohse; Bradley C Leibovich; Michael L Blute; John C Cheville; George Vasmatzis
Journal:  Clin Cancer Res       Date:  2005-07-15       Impact factor: 12.531

7.  Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells.

Authors:  Joseph S Kruger; Kaladhar B Reddy
Journal:  Mol Cancer Res       Date:  2003-09       Impact factor: 5.852

8.  Expression of heat shock protein 27 in human renal cell carcinoma.

Authors:  Cecilia Sarto; Cristina Valsecchi; Fulvio Magni; Lucia Tremolada; Carmelo Arizzi; Nicoletta Cordani; Stefano Casellato; Giancarlo Doro; Paolo Favini; Roberto A Perego; Francesca Raimondo; Stefano Ferrero; Paolo Mocarelli; Marzia Galli-Kienle
Journal:  Proteomics       Date:  2004-08       Impact factor: 3.984

9.  Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor.

Authors:  James R Vasselli; Joanna H Shih; Shuba R Iyengar; Jodi Maranchie; Joseph Riss; Robert Worrell; Carlos Torres-Cabala; Ray Tabios; Andra Mariotti; Robert Stearman; Maria Merino; McClellan M Walther; Richard Simon; Richard D Klausner; W Marston Linehan
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-30       Impact factor: 11.205

10.  Proteomic identification of interleukin-2 therapy response in metastatic renal cell cancer.

Authors:  Jon Jones; Hasan H Otu; Franck Grall; Dimitrios Spentzos; Handan Can; Manuel Aivado; Arie S Belldegrun; Allan J Pantuck; Towia A Libermann
Journal:  J Urol       Date:  2007-12-20       Impact factor: 7.450
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  1 in total

1.  Prediction and diagnosis of renal cell carcinoma using nuclear magnetic resonance-based serum metabolomics and self-organizing maps.

Authors:  Hong Zheng; Jiansong Ji; Liangcai Zhao; Minjiang Chen; An Shi; Linlin Pan; Yiran Huang; Huajie Zhang; Baijun Dong; Hongchang Gao
Journal:  Oncotarget       Date:  2016-09-13
  1 in total

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