Literature DB >> 12209149

Clinical proteomics: translating benchside promise into bedside reality.

Emanuel F Petricoin1, Kathryn C Zoon, Elise C Kohn, J Carl Barrett, Lance A Liotta.   

Abstract

The ultimate goal of proteomics is to characterize the information flow through protein networks. This information can be a cause, or a consequence, of disease processes. Clinical proteomics is an exciting new subdiscipline of proteomics that involves the application of proteomic technologies at the bedside, and cancer, in particular, is a model disease for studying such applications. Here, we describe proteomic technologies that are being developed to detect cancer earlier, to discover the next generation of targets and imaging biomarkers, and finally to tailor the therapy to the patient.

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Year:  2002        PMID: 12209149     DOI: 10.1038/nrd891

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


  92 in total

Review 1.  Clinical applications of proteomics: proteomic pattern diagnostics.

Authors:  Emanuel E Petricoin; Cloud P Paweletz; Lance A Liotta
Journal:  J Mammary Gland Biol Neoplasia       Date:  2002-10       Impact factor: 2.673

Review 2.  Proteomics for protein expression profiling in neuroscience.

Authors:  Willard M Freeman; Scott E Hemby
Journal:  Neurochem Res       Date:  2004-06       Impact factor: 3.996

Review 3.  Disease proteomics toward bedside reality.

Authors:  Toshihide Nishimura; Atsushi Ogiwara; Kiyonaga Fujii; Takao Kawakami; Takeshi Kawamura; Hisae Anyouji; Harubumi Kato
Journal:  J Gastroenterol       Date:  2005-03       Impact factor: 7.527

Review 4.  Multiplexed protein measurement: technologies and applications of protein and antibody arrays.

Authors:  Stephen F Kingsmore
Journal:  Nat Rev Drug Discov       Date:  2006-04       Impact factor: 84.694

Review 5.  Proteomic technology for biomarker profiling in cancer: an update.

Authors:  Moulay A Alaoui-Jamali; Ying-jie Xu
Journal:  J Zhejiang Univ Sci B       Date:  2006-06       Impact factor: 3.066

6.  Exocrine pancreatic cancer: symptoms at presentation and their relation to tumour site and stage.

Authors:  Miquel Porta; Xavier Fabregat; Núria Malats; Luisa Guarner; Alfredo Carrato; Ana de Miguel; Laura Ruiz; Manuel Jariod; Sergi Costafreda; Susana Coll; Juan Alguacil; Josep M Corominas; Ricard Solà; Antonio Salas; Francisco X Real
Journal:  Clin Transl Oncol       Date:  2005-06       Impact factor: 3.405

Review 7.  Microfluidics for drug discovery and development: from target selection to product lifecycle management.

Authors:  Lifeng Kang; Bong Geun Chung; Robert Langer; Ali Khademhosseini
Journal:  Drug Discov Today       Date:  2007-11-26       Impact factor: 7.851

8.  Alteration of the bioenergetic phenotype of mitochondria is a hallmark of breast, gastric, lung and oesophageal cancer.

Authors:  Antonio Isidoro; Marta Martínez; Pedro L Fernández; Alvaro D Ortega; Gema Santamaría; Margarita Chamorro; John C Reed; José M Cuezva
Journal:  Biochem J       Date:  2004-02-15       Impact factor: 3.857

Review 9.  Proteomics in cancer screening and management in gynecologic cancer.

Authors:  Wei Hu; Weiguo Wu; Ryuji Kobayashi; John J Kavanagh
Journal:  Curr Oncol Rep       Date:  2004-11       Impact factor: 5.075

10.  Tailoring of the nanotexture of mesoporous silica films and their functionalized derivatives for selectively harvesting low molecular weight protein.

Authors:  Ye Hu; Ali Bouamrani; Ennio Tasciotti; Li Li; Xuewu Liu; Mauro Ferrari
Journal:  ACS Nano       Date:  2010-01-26       Impact factor: 15.881

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